Friedrichs, M. (2023). A web-based annotation tool for clinical trial failure reasons. GMS Medizinische Informatik, Biometrie Und Epidemiologie, 19, Doc02. doi: 10.3205/mibe000241

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Trial ID Phase Status Type
Results Reported Result Refs Exist Enrollment From To
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7805 Trials matched filter criteria

Status:   Withdrawn   Suspended   Terminated
Trial Updated /
Type
Status Phase Were
Results
Reported
Reported
Actual
Enrollment
(MeSH) Terms Why Stopped
Limitations And Caveats
Annotator decisions
NCT01994291
2013-003147-27
Details
2016-10-17
Interventional
2199 
Ranibizumab
Edema Macular Edema Macular Edema, …
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NCT01068756
Details
2016-10-17
Interventional
114 
Dapagliflozin Rifampin
Diabetes Mellit… Type 2 Diabetes…
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NCT00726505
Details
2016-10-17
Interventional
11 
Dapagliflozin
Diabetes, NOS
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NCT01661140
2011-005260-20
Details
2016-10-14
Interventional
4427 
Methotrexate
Arthritis Arthritis, Rheu… Rheumatoid Arth…
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NCT01050426
Details
2016-10-14
Interventional
217 
Cetuximab Leucovorin Levoleucovorin
Pancreatic Neop… Pancreatic Canc…
Data from other trials failed to demonstrate meaningful survival advantage
-
NCT00788606
Details
2016-10-14
Interventional
27 
Bevacizumab Rituximab
Lymphoma Lymphoma, B-Cel… Lymphoma, Large… Lymphoma, Non-H… B-cell Lymphoma Non-Hodgkin's L…
Toxicity and efficacy data from another trial
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NCT02485080
Details
2016-10-13
Interventional
40 
Simeprevir Sofosbuvir
Hepatitis Hepatitis C Hepatitis C, Ch… PT-NANBH
Withdrawn due to lack of resources
-
NCT01123473
2009-011580-36
Details
2016-10-12
Interventional
2
[1 Refs]
29 
Capecitabine Epirubicin Fluorouracil Lapatinib
Adenocarcinoma Esophageal Neop… Stomach Neoplas… Adenocarcinoma … Gastric Cancer
company withdrew interest
-
NCT02376972
Details
2016-10-10
Interventional
2392 
Metronidazole Rifaximin
Vaginal Disease… Vaginosis, Bact… BACTERIAL VAGIN…
According to the Recommendation of the Indipendent Data Monitoring Committee
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NCT00597116
2007-003633-16
Details
2016-10-10
Interventional
225 
Vinorelbine
Mesothelioma Mesothelioma, M…
Recruitment stopped according to early stopping rule (by protocol)
Early termination leading to small number of subjects analyzed.
NCT02605356
2015-000427-82
Details
2016-10-07
Interventional
1/20 
Bortezomib Dexamethasone Radium Ra 223 d…
Multiple Myelom… Neoplasms, Plas…
Study restarted under new study number 18987
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NCT01405742
Details
2016-10-07
Interventional
34 
Factor VIII
Hemophilia A Severe Hemophil…
study was non-feasible per DSMB
-
NCT00912899
Details
2016-10-07
Interventional
112 
Noscapine
Multiple Myelom… Neoplasms, Plas… Refractory Mult…
Terminated early due to lack of clinical response.
-
NCT00316680
Details
2016-10-07
Interventional
3-
Vaccines
Diphtheria Hepatitis Hepatitis A Hepatitis B Haemophilus Inf… Tetanus Whole Cell Pert…
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NCT02380313
Details
2016-10-06
Interventional
10 
Prednisone
Cancer
Study cancelled: Withdrawn before enrollment of any participants
-
NCT01039103
2009-013884-21
Details
2016-10-06
Interventional
215 
Methylprednisol… Methylprednisol… Methylprednisol… Prednisolone Prednisolone ac… Prednisolone he… Prednisolone ph…
Multiple Sclero… Multiple Sclero… Sclerosis Syndrome Acute Exacerbat… Clinically Isol…
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NCT02263677
Details
2016-10-05
Interventional
40 
Sitagliptin Pho…
Fatty Liver Liver Diseases Non-alcoholic F… Type 2 Diabetes
Technical difficulties have caused this study to be terminated
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NCT02201524
Details
2016-10-05
Interventional
259 
Abrocitinib
Psoriasis Plaque Psoriasi…
Study terminated 26 June 2015 due to changes in the drug development portfolio. This study was not terminated for reasons of safety and/or efficacy
The study was terminated early due to changes in the prioritization of the drug development portfolio and the early termination was not safety related.
NCT00956709
Details
2016-10-05
Interventional
435 
Levobupivacaine Ropivacaine
Nerve Block
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NCT01219062
Details
2016-10-04
Interventional
410 
Bupivacaine Morphine
Femoral Neck Fr… Pain, Postopera… Femoral Neck Fr…
Surgeon team were not happy with the study protocol, the periarticular injection of local anesthetics
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