Friedrichs, M. (2023). A web-based annotation tool for clinical trial failure reasons. GMS Medizinische Informatik, Biometrie Und Epidemiologie, 19, Doc02. doi: 10.3205/mibe000241

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Trial ID Phase Status Type
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7805 Trials matched filter criteria

Status:   Withdrawn   Suspended   Terminated
Trial Updated /
Type
Status Phase Were
Results
Reported
Reported
Actual
Enrollment
(MeSH) Terms Why Stopped
Limitations And Caveats
Annotator decisions
NCT01377376
Details
2016-12-07
Interventional
3-
Erlotinib Hydro…
Carcinoma, Non-… Lung Neoplasms Non-small-cell …
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NCT00752986
2008-000579-12
Details
2016-12-05
Interventional
239 
Fulvestrant
Breast Neoplasm… Breast Cancer
-
-
NCT01746602
Details
2016-12-02
Interventional
338 
Timolol
Glaucoma Healthy
-
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NCT01457001
Details
2016-12-01
Interventional
3284 
Vitamin D
Kidney Failure,… Chronic Renal F…
-
-
NCT00069329
Details
2016-12-01
Interventional
1/243 
Interleukin 1 R…
Arthropathy, Ne… Cryopyrin-Assoc… Joint Diseases Nervous System … Papilledema Urticaria
data submitted for Food and Drug Administration (FDA) approval
Data reported is on 26 patients who completed their 3 year assessment and 20 of these patients also completed their 5 year assessment.
NCT00040391
Details
2016-12-01
Interventional
2-
Fluorouracil Irinotecan Leucovorin
Colorectal Neop… Diarrhea
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NCT02434523
Details
2016-11-30
Interventional
2/330 
Amitriptyline
Laryngeal Disea… Laryngitis Chronic Larynge…
concern regarding study design
Early termination leading to small numbers of subjects analyzed
NCT00699842
Details
2016-11-29
Interventional
1/28 
Lenalidomide
Myelodysplastic… Preleukemia Syndrome Low to Intermed… MDS Myelodysplastic… Non-deletion 5q
Administratively terminated per FDA recommendation
Study was terminated as the objectives of this study have already been addressed in a larger study, and therefore the study is unlikely to yield any new information. The study closed before any data for the outcome measures was able to be collected.
NCT00359671
Details
2016-11-29
Interventional
1-
Docetaxel
Neoplasms Advanced Solid …
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NCT01450696
2011-001526-19
Details
2016-11-28
Interventional
3296 
Capecitabine Trastuzumab
Stomach Neoplas… Gastric Cancer
futility following planned interim analysis
Trial was stopped for futility based on pre-planned interim analysis results.
NCT02963103
Details
2016-11-23
Interventional
413 
Tacrolimus
Kidney Transpla…
Sponsor decision to terminate the study because subject enrollment was difficult.
-
NCT02618499
Details
2016-11-23
Interventional
3180 
Oxytocin
Placental Trans…
Futility suggested by DSMC
-
NCT01561950
Details
2016-11-23
Interventional
191 
Clopidogrel
Hemorrhage Haemostasis Healthy
-
-
NCT02599077
Details
2016-11-22
Interventional
2/3
[1 Refs]
-
Dienogest Levonorgestrel
Endometriosis
-
-
NCT00912444
Details
2016-11-22
Interventional
3102 
Cyclophosphamid… Docetaxel Doxorubicin Epirubicin
Breast Neoplasm… Breast Cancer
TAC treatment was associated with better survial outcome compared with TC treatment, we terminated recruiting and waiting for longer follow up period.
-
NCT01886573
Details
2016-11-18
Interventional
1-
Azacitidine Entinostat Histone Deacety…
Carcinoma Carcinoma, Non-… Lung Neoplasms Stage IA Non-Sm… Stage IB Non-Sm… Stage IIA Non-S… Stage IIB Non-S… Stage IIIA Non-…
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NCT01329250
Details
2016-11-18
Interventional
49 
Moxifloxacin
Tuberculosis
slow enrolment of patients and new insights
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NCT00316212
Details
2016-11-18
Interventional
2-
INS 50589
Coronary Diseas…
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NCT01950195
Details
2016-11-15
Interventional
14 
Ipilimumab
Melanoma Neoplasm Metast… Newly Diagnosed…
Local IRB required us to submit amendment as a separate study.
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NCT00557219
Details
2016-11-15
Interventional
360 
Fenoldopam Ketanserin
Acute Kidney In… Renal Insuffici… Acute Renal Fai…
Main cooperator finished cooperation
-