Friedrichs, M. (2023). A web-based annotation tool for clinical trial failure reasons. GMS Medizinische Informatik, Biometrie Und Epidemiologie, 19, Doc02. doi: 10.3205/mibe000241

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7805 Trials matched filter criteria

Status:   Withdrawn   Suspended   Terminated
Trial Updated /
Type
Status Phase Were
Results
Reported
Reported
Actual
Enrollment
(MeSH) Terms Why Stopped
Limitations And Caveats
Annotator decisions
NCT02795884
Details
2016-12-30
Interventional
30 
Cisplatin Erlotinib Hydro… Pemetrexed Vinorelbine
NSCLC
Because of reconsideration of using erlotinib(EGFR Tyrosine kinase inhibitor) as adjuvant aim
-
NCT01167192
Details
2016-12-30
Interventional
210 
Carboplatin
Breast Neoplasm… Triple Negative…
-
-
NCT00891995
NCT00505206
Details
2016-12-30
Interventional
2/3
[1 Refs]
71 
Insulin
Diabetes Mellit… Diabetes Mellit… Type 1 Diabetes
Primary outcome evaluation determined lack of treatment group difference
-
NCT01984255
Details
2016-12-29
Interventional
13 
Bavituximab Ipilimumab
Melanoma
standard of care improved combination treatment of ipilimumab plus nivolumab.
-
NCT01710228
Details
2016-12-29
Interventional
20 
Methylprednisol… Methylprednisol… Methylprednisol… Prednisolone Prednisolone ac… Prednisolone he… Prednisolone ph…
Multiple Sclero… Multiple Sclero…
sponsor stopped
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NCT00362869
Details
2016-12-26
Interventional
15 
Levofloxacin
Escherichia col… Escherichia Col…
-
-
NCT01816789
Details
2016-12-23
Interventional
4194 
Buserelin
In Vitro Fertil… Ovarian Stimula…
Optimal response: 63% nomogram, 42% controls, overcoming the stopping rule for interim analysis
-
NCT02396030
Details
2016-12-20
Interventional
462 
Magnesium Sulfa…
Pre-Eclampsia Preeclampsia
After recommendation because of the impossibility to end study with 1 center only. Outcomes of patients already included will be evaluated.
-
NCT02997059
2008-000717-30
Details
2016-12-19
Interventional
235 
Fluconazole
Crohn Disease Crohn's Disease…
Limited recourse to intestinal resection due to new management of CD
-
NCT00977145
Details
2016-12-16
Interventional
111 
Interferon-gamm…
Melanoma
Closed short of the enrollment goal, due to slow enrollment and adequate data to address endpoints
-
NCT01600053
Details
2016-12-15
Interventional
211 
Lenalidomide
Leukemia Leukemia, Lymph… Leukemia, Lymph… Chronic Lymphoc…
interim analysis showed that the trial will not meet the interim endpoint.
-
NCT00081224
Details
2016-12-15
Interventional
23 
Capecitabine Celecoxib
Adenocarcinoma Colorectal Canc…
-
-
NCT00068666
Details
2016-12-15
Interventional
2
[1 Refs]
41 
Temozolomide
Melanoma Melanoma (Skin) Metastatic Canc…
-
-
NCT01410565
Details
2016-12-13
Interventional
366 
Apaziquone
Non-Muscle Inva… Urinary Bladder… Bladder Cancer
Business reason
-
NCT00352755
Details
2016-12-13
Interventional
218 
Fluorouracil Leucovorin Oxaliplatin
Carcinoma Peritoneal Neop… Pseudomyxoma Pe…
after interim analysis it was determined that the risks were too great in comparision to the results
-
NCT00352690
Details
2016-12-12
Interventional
210 
Carboplatin Paclitaxel Paclitaxel poli…
Carcinoma, Non-…
Safety of patients
(3) grade 5 serious adverse events occurred and led to the study closing early for the safety of participants.
NCT02125266
Details
2016-12-09
Interventional
1/27 
Methotrexate
Pars Planitis Uveitis Uveitis, Interm… Uveitis, Poster…
Study terminated due to unacceptable frequency of drug related adverse events
-
NCT01324635
Details
2016-12-09
Interventional
117 
Histone Deacety… Panobinostat
Brain Neoplasms Meningioma Neoplasm Metast… Brain Metastasi… High-grade Meni… Recurrent Gliom…
Arm A - reached goal; Arm B - poor accrual
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NCT02035345
Details
2016-12-08
Interventional
415 
Carboplatin
Carcinoma, Ovar… Hypersensitivit… Ovarian Neoplas… Platinum Sensit… Recurrent Ovari…
Extended Carboplatin Infusion did not Reduce Frequency of Hypersensitivity Reactions
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NCT02631473
Details
2016-12-07
Interventional
1-
Efavirenz Lopinavir Ritonavir
HIV
Study is on hold whilst a grant application for further funding is put together
-