Friedrichs, M. (2023). A web-based annotation tool for clinical trial failure reasons. GMS Medizinische Informatik, Biometrie Und Epidemiologie, 19, Doc02. doi: 10.3205/mibe000241

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Trial ID Phase Status Type
Results Reported Result Refs Exist Enrollment From To
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7805 Trials matched filter criteria

Status:   Withdrawn   Suspended   Terminated
Trial Updated /
Type
Status Phase Were
Results
Reported
Reported
Actual
Enrollment
(MeSH) Terms Why Stopped
Limitations And Caveats
Annotator decisions
NCT00000310
Details
2017-01-16
Interventional
2-
Risperidone
Cocaine-Related…
-
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NCT00812812
Details
2017-01-13
Interventional
456 
Paroxetine
Depression Depressive Diso…
-
-
NCT01221740
Details
2017-01-12
Interventional
30 
Levomilnacipran Milnacipran
Back Pain
Company decided to discontinue
-
NCT00218049
Details
2017-01-12
Interventional
13 
Vanoxerine
Cocaine-Related… Cocaine Abuse
Issue of priority of resources
-
NCT00046813
Details
2017-01-12
Interventional
4-
Nicotine
Psychotic Disor… Schizophrenia Tobacco Use Dis…
Interim data analysis showed no effect between treatment groups
-
NCT00000313
Details
2017-01-12
Interventional
1-
Fenfluramine
Cocaine-Related…
-
-
NCT02439138
Details
2017-01-11
Interventional
25 
Idelalisib
Waldenstrom Mac… Waldenstrom's M…
Safety issues from trials in CLL
This study was terminated early due to safety concerns from the previously untreated CLL experience. All participants who remained on study at that time were permanently removed from protocol therapy. The median time on protocol therapy was 1 cycle
NCT02319200
Details
2017-01-11
Interventional
311 
Metformin
Carcinoma Carcinoma, Hepa… Fibrosis Hepatitis C Hepatitis C, Ch… Liver Cirrhosis Cirrhosis Hepatocellular …
Decision of investigator
-
NCT01201538
Details
2017-01-11
Interventional
22 
Nilotinib
Neurilemmoma Neuroma, Acoust… Growing Vestibu…
Study PI passed away We had trouble recruiting for the drug arm
-
NCT01148992
Details
2017-01-11
Interventional
116 
Lofexidine
Cocaine-Related… Cocaine Related…
-
-
NCT01060865
Details
2017-01-11
Interventional
450 
Aliskiren
Hypertension Blood Pressure,…
The participants signed an old version of the informed consent.
-
NCT00090194
Details
2017-01-11
Interventional
256 
Antibodies Immunoglobulins Immunoglobulins… Rho(D) Immune G… gamma-Globulins
Kidney Failure,… Renal Insuffici…
-
-
NCT00045591
Details
2017-01-11
Interventional
239 
Celecoxib
Breast Neoplasm… Breast Cancer
-
-
NCT00000936
Details
2017-01-11
Interventional
3292 
Cyclosporine Cyclosporins
Kidney Transpla…
-
-
NCT02310568
Details
2017-01-09
Interventional
290 
PF-06372865
Anxiety Disorde… Generalized Anx…
Study recruitment was terminated on 24 June 2015, due to a Pfizer business decision. This study was not terminated for reasons of safety or efficacy
All 34 centres who enrolled subjects were terminated due to internal sponsor portfolio prioritization. The decision to terminate the study was not due to any safety concern or change in the benefit:risk assessment of PF-06372865
NCT01817777
Details
2017-01-09
Interventional
431 
Metformin
Diabetes Mellit… Diabetes Mellit…
It's no longer feasible to continue to recruit patients into the study as severe recruitment difficulties have been experienced since the study start
-
NCT02213744
Details
2017-01-06
Interventional
2/3113 
Capecitabine Gemcitabine Trastuzumab Vinorelbine
Breast Neoplasm… Breast Cancer HER2 Positive B…
Felt not to show benefit over control per DMC and confirmed via futility analysis
-
NCT01708798
Details
2017-01-05
Interventional
2/344 
Eplerenone
Breast Neoplasm… Breast Cancer
Futility
-
NCT01383148
Details
2017-01-05
Interventional
2/3222 
Carboplatin Cisplatin Gemcitabine Paclitaxel Pemetrexed
Carcinoma, Non-… Non-Small-Cell …
-
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NCT00663910
Details
2017-01-02
Interventional
118 
Aminolevulinic …
Skin Neoplasms Non-melanomatou…
Of the 8 histologically proven tumors, detection of PpIX proved to be ambiguous.
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