Friedrichs, M. (2023). A web-based annotation tool for clinical trial failure reasons. GMS Medizinische Informatik, Biometrie Und Epidemiologie, 19, Doc02. doi: 10.3205/mibe000241

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Trial ID Phase Status Type
Results Reported Result Refs Exist Enrollment From To
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7805 Trials matched filter criteria

Status:   Withdrawn   Suspended   Terminated
Trial Updated /
Type
Status Phase Were
Results
Reported
Reported
Actual
Enrollment
(MeSH) Terms Why Stopped
Limitations And Caveats
Annotator decisions
NCT02074007
Details
2017-01-24
Interventional
3178 
Benzocaine
Otitis Otitis Media Acute Otitis Me…
primary outcome measure not met
-
NCT01718808
Details
2017-01-24
Interventional
224 
Capecitabine Cetuximab
Colorectal Neop… Metastatic Colo…
FU for 3 years from randomization as initially planned is stopped as we do not expect any changes to the endpoints in the future after one year of FU.
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NCT00927290
2008-006225-14
Details
2017-01-24
Interventional
340 
Pioglitazone
Hepatitis Hepatitis A Hepatitis C Hepatitis C, Ch… Hepatitis, Chro… Insulin Resista… Chronic Hepatit…
Suspension of use of medicine containing Pioglitazone by French regulatory agency
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NCT00571285
Details
2017-01-24
Interventional
431 
Cholecalciferol Ergocalciferols Vitamin D Vitamins
Parkinson Disea… Parkinson's Dis…
-
-
NCT00304317
Details
2017-01-24
Interventional
40 
Celecoxib
Calculi Renal Colic Ureteral Calcul… Ureterolithiasi…
PI is no longer at the University of Minnesota
-
NCT02527213
Details
2017-01-23
Interventional
340 
Sodium thiosulf…
Calciphylaxis Calcific Uremic…
Company decision
-
NCT01474122
Details
2017-01-23
Interventional
3
[1 Refs]
265 
Macitentan
Scleroderma, Di… Scleroderma, Sy… Sclerosis Skin Ulcer Ulcer Digital Ulcers
company decision
-
NCT00462228
Details
2017-01-23
Interventional
411 
Memantine
Brain Injuries Brain Injuries,… Wounds and Inju… Traumatic Brain…
The study was stopped due to a lack of additional subjects.
The enrollment goal for the study was 20 subjects. The study included 11 subjects but was terminated due to a lack of additional subjects.
NCT02586610
Details
2017-01-20
Interventional
20 
Capecitabine Pembrolizumab
Rectal Neoplasm… Rectal Cancer Rectal Neoplasm
Dr. Rahma decided to run the study through a different group
-
NCT00694408
Details
2017-01-20
Interventional
315 
Hydrocortisone Hydrocortisone … Hydrocortisone … Hydrocortisone … Methylprednisol… Methylprednisol… Methylprednisol… Prednisolone Prednisolone ac… Prednisolone he… Prednisolone ph…
Evidence of Liv…
Study terminated due to withdrawal from market of Daclizumab
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NCT00680485
Details
2017-01-20
Interventional
1-
Ketoconazole
Bacterial Infec… Communicable Di… Infections Bacterial Infec… Infections, Bac…
-
-
NCT02390440
Details
2017-01-19
Interventional
40 
Bupivacaine
Rib Fractures Pain
Did not obtain an IND.
-
NCT01930890
2013-000594-69
Details
2017-01-18
Interventional
287 
Mycophenolic Ac…
Lupus Nephritis Nephritis
Results from pre-specified criteria in study NCT01499355 (211LE201) did not demonstrate sufficient efficacy to warrant continuation of the study
Study was terminated based on the pre-specified, blinded futility analysis of Study 211LE201 (NCT01499355), which did not demonstrate sufficient efficacy to warrant continuation of the studies. Study was not terminated based on safety considerations.
NCT01499355
2011-002159-32
Details
2017-01-18
Interventional
2276 
Mycophenolic Ac…
Lupus Nephritis Nephritis
Results from pre-specified criteria did not demonstrate sufficient efficacy to warrant continuation of the study.
Study was terminated based on the review of results following the prespecified, blinded futility analysis, which did not demonstrate sufficient efficacy to warrant continuation of the study. Study was not terminated based on safety considerations.
NCT00123903
Details
2017-01-18
Interventional
3-
Carvedilol Lisinopril Metoprolol
Heart Failure Hypertension Heart Failure, …
-
-
NCT02129062
Details
2017-01-16
Interventional
23 
Ibrutinib
Leukemia Leukemia, Lymph… Precursor Cell … Adult B Acute L… Adult B Acute L… Recurrent Adult…
Slow accrual.
-
NCT01695330
Details
2017-01-16
Interventional
25 
Bortezomib
Multiple Myelom… Neoplasms, Plas…
Terminated by Sponsor of this study.
-
NCT01446250
Details
2017-01-16
Interventional
38 
Peginterferon a… Ribavirin
Hepatitis Hepatitis A Hepatitis C Hepatitis C, Ch… Hepatitis, Chro…
-
Due to the early termination of study enrollment and discontinuation of alisporivir treatment, Amendment 1 changed the number of study arms to 2, combining Arms A and B, and none of the planned outcome measures could be evaluated.
NCT00438139
Details
2017-01-16
Interventional
1-
Dronabinol
Marijuana Abuse Marijuana Depen…
-
-
NCT00000577
Details
2017-01-16
Interventional
30 
Adrenergic Agen… Adrenergic beta… Albuterol Colchicine Hormones
Asthma Lung Diseases
Record is an ACRN grant summary & not reflective of an individual trial. All ACTs conducted by ACRN were individually registered on the PRS.
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