Friedrichs, M. (2023). A web-based annotation tool for clinical trial failure reasons. GMS Medizinische Informatik, Biometrie Und Epidemiologie, 19, Doc02. doi: 10.3205/mibe000241

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Trial ID Phase Status Type
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7805 Trials matched filter criteria

Status:   Withdrawn   Suspended   Terminated
Trial Updated /
Type
Status Phase Were
Results
Reported
Reported
Actual
Enrollment
(MeSH) Terms Why Stopped
Limitations And Caveats
Annotator decisions
NCT02503462
Details
2017-02-02
Interventional
47 
Cobicistat Darunavir Ritonavir
AIDS Dementia C… AIDS-related De…
No additional patients fulfilling the inclusion criteria
-
NCT02050724
Details
2017-02-02
Interventional
211 
Technetium Tc 9…
Bronchial Neopl… Multiple Pulmon… Solitary Pulmon…
Ende of part 1. Only few patients in part 2 enrolled
-
NCT00301106
Details
2017-02-02
Interventional
12 
Interleukin-12
Breast Neoplasm… Breast Cancer Metastatic Canc…
protocol underwent significant revisions, decision made to terminate study and open as new study listed NCT00849459
-
NCT02400385
Details
2017-02-01
Interventional
20 
Nivolumab Sunitinib
Melanoma
With recent advances in immunotherapy scientific question not significant
-
NCT02096315
Details
2017-02-01
Interventional
2-
Murepavadin
Bronchiectasis Fibrosis Infections Respiratory Tra… Lower Respirato…
-
-
NCT01703260
Details
2017-02-01
Interventional
220 
Pioglitazone
Fatty Liver Non-alcoholic F… Nonalcoholic St…
Company decision; No safety or efficacy concerns (see detailed description)
-
NCT00362700
Details
2017-02-01
Interventional
2-
Clevudine
Hepatitis Hepatitis B
-
-
NCT00362505
Details
2017-02-01
Interventional
3-
Clevudine
Hepatitis Hepatitis B
-
-
NCT00313287
Details
2017-02-01
Interventional
3-
Clevudine
Hepatitis Hepatitis B
-
-
NCT00313274
Details
2017-02-01
Interventional
3-
Clevudine
Hepatitis Hepatitis B
-
-
NCT00927147
Details
2017-01-31
Interventional
1/217 
Cetuximab
Head and Neck N… Head and Neck C…
The neutron facility closed down for financial reasons.
-
NCT02417129
2014-004544-36
Details
2017-01-30
Interventional
32 
Rituximab
Lymphoma Lymphoma, Folli… Lymphoma, Non-H…
-
As the program was prematurely discontinued and only two patients were randomized at the time of discontinuation, the planned statistical analysis was not performed and safety data are therefore presented in this abbreviated Clinical Trial Report.
NCT01389076
Details
2017-01-30
Interventional
222 
Methotrexate Tositumomab I-1…
Lymphoma Lymphoma, Folli… Follicular Lymp…
Bexxar isn't being produced by the manufacturer as of Feb. 2014
This trial was abandoned prematurely due to the withdrawal of Bexxar by the manufacturer and failure to find another supplier.
NCT01957410
Details
2017-01-27
Interventional
213 
Ketamine
Depression Depressive Diso… Depressive Diso… Major Depressiv…
Clinical Team decision to terminate the study after the results from Cohort 1 did not support conducting Cohort 2.
Study was planned as open label treatment phase (Cohort 1) and double blind treatment phase (Cohort 2). However, study was terminated after completion of Cohort 1.
NCT01717040
Details
2017-01-27
Interventional
437 
Pioglitazone
Bipolar Disorde… Insulin Resista…
The study ended early due to budgetary issues
-
NCT02179151
Details
2017-01-26
Interventional
3108 
CKD732
Prader-Willi Sy… Syndrome Obesity
FDA Clinical Hold
-
NCT01784900
2012-000475-17
Details
2017-01-26
Interventional
226 
Antibodies, Bis… Catumaxomab
Carcinoma Peritoneal Neop… Patients With G…
-
-
NCT00361114
Details
2017-01-26
Interventional
3112 
Chlorproguanil Dapsone Fanasil, pyrime… Pyrimethamine Sulfadoxine
Malaria
SP arms were stopped due to high levels of treatment failure.CD not available.
-
NCT02204345
2014-001498-15
Details
2017-01-25
Interventional
1/212 
Carboplatin Paclitaxel
Carcinoma, Non-… Lung Neoplasms Squamous Non-Sm…
-
-
NCT02096133
2014-000728-97
Details
2017-01-25
Interventional
254 
Cholecalciferol Vitamin D
Multiple Sclero… Sclerosis
difficulties with inclusion
-