Friedrichs, M. (2023). A web-based annotation tool for clinical trial failure reasons. GMS Medizinische Informatik, Biometrie Und Epidemiologie, 19, Doc02. doi: 10.3205/mibe000241

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Trial ID Phase Status Type
Results Reported Result Refs Exist Enrollment From To
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7805 Trials matched filter criteria

Status:   Withdrawn   Suspended   Terminated
Trial Updated /
Type
Status Phase Were
Results
Reported
Reported
Actual
Enrollment
(MeSH) Terms Why Stopped
Limitations And Caveats
Annotator decisions
NCT00324324
Details
2017-05-09
Interventional
3
[1 Refs]
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Moxifloxacin Norgestimate, e…
Bacterial Infec… Breast Neoplasm… Communicable Di… Infections Leukemia Lymphoma Multiple Myelom… Myelodysplastic… Myelodysplastic… Myeloproliferat… Neoplasms Neoplasms, Germ… Neoplasms, Plas… Neuroblastoma Plasmacytoma Preleukemia Syndrome Trophoblastic N… Breast Cancer Chronic Myelopr… Gestational Tro… Infection Multiple Myelom… Myelodysplastic… Ovarian Cancer Testicular Germ…
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NCT00140920
Details
2017-05-09
Interventional
411 
Diclofenac Rofecoxib
Pain, Postopera… Pain
Recruitment/study discontinued after withdrawal of marketing authorisation. No data entered.
-
NCT02213029
Details
2017-05-08
Interventional
133 
Oxytocin
Embryo Transfer
-
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NCT00915590
Details
2017-05-08
Interventional
1/210 
Interleukin 1 R…
Corneal Neovasc… Neovascularizat…
-
Enrollment goal for this study was set at 20 participants (10 for each treatment arm). After an interim analysis, the Principal Investigator decided to terminate the study and stop enrollment.
NCT02544269
2015-003498-13
Details
2017-05-05
Interventional
48 
Bupivacaine Ropivacaine
Total Hip Repla…
After pilot study no difference in the primary end point was found between the two primary. Non-inferiority trial not deemed feasible.
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NCT02428231
2014-004562-22
Details
2017-05-05
Interventional
362 
Dimethyl Fumara…
Multiple Sclero… Sclerosis
Sponsor decision
The Sponsor decided to terminate the study as a result of an evaluation of ongoing development programs.
NCT02368249
Details
2017-05-05
Interventional
20 
Terlipressin
Renal Insuffici… Kidney Failure
no focus on this topic
-
NCT01937364
Details
2017-05-05
Interventional
217 
Baclofen
Alcoholism Alcohol Withdra…
The enrollment in the study was too limited for meaningful data analysis.
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NCT01353378
Details
2017-05-05
Interventional
40 
Dexmedetomidine
Delirium Emergence Delir…
The study was not approved by Hospital's Medical Ethics Committee.
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NCT02516436
Details
2017-05-04
Interventional
30 
Buprenorphine
Opioid-Related … Opioid Dependen…
FDA did not require a clinical trial for indication.
-
NCT01713803
Details
2017-05-04
Interventional
30 
Buprenorphine Naloxone
Opioid-Related … Opioid Dependen…
FDA did not require a clinical trial for indication.
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NCT02791919
Details
2017-05-03
Interventional
10 
Adavosertib Cytarabine Fludarabine Fludarabine pho… Lenograstim
Leukemia Leukemia, Myelo… Leukemia, Myelo… Recurrence CNS 2a CNS 2b CNS 2c CNS1 Recurrent Adult… Recurrent Child…
Other - Protocol moved to Disapproved
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NCT02753218
Details
2017-05-03
Interventional
112 
Midazolam
Psoriasis Psoriasis Vulga…
Due to tolerability issues related to the dose titration, unexpected withdrawals were observed and it was unlikely for the trial to meet its objectives
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NCT02359500
Details
2017-05-03
Interventional
171 
Edotreotide Octreotide
Carcinoid Tumor Neoplasms Neuroendocrine … Carcinoid Tumor…
compound no longer available
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NCT02206776
Details
2017-05-03
Interventional
22 
Ketamine Midazolam
Compulsive Pers… Obsessive-Compu…
poor tolerability and low enrollment rate
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NCT01379521
Details
2017-05-03
Interventional
265 
Everolimus
Carcinoma Carcinoma, Hepa… Hepatocellular …
The study was terminated due to low enrollment. This resulted in the study being underpowered and inconclusive.
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NCT01002339
Details
2017-05-03
Interventional
4
[1 Refs]
134 
Basiliximab Cyclosporine Mycophenolic Ac… Prednisone Tacrolimus
Diabetes Mellit… Diabetes Mellit… Diabetes Mellit…
Terminated: higher rate of acute rejection in the Cyclosporin A group
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NCT02227914
2014-003149-85
Details
2017-05-02
Interventional
1/20 
Sorafenib
Carcinoma Carcinoma, Hepa… Advanced Hepato…
Study stopped due to administrative reasons
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NCT00974675
2006-003199-36
Details
2017-05-02
Interventional
123 
Antibodies, Mon…
Asthma Moderate Asthma
Study recruitment was terminated before the planned number of subjects was enrolled in CAT-354 10 mg/kg group due to the slow recruitment rate.
Recruitment to the study was terminated before the planned number of participants was enrolled in CAT-354 10 mg/kg group due to the slow recruitment rate.
NCT02614586
Details
2017-05-01
Interventional
111 
Ondansetron
Schizophrenia
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