Friedrichs, M. (2023). A web-based annotation tool for clinical trial failure reasons. GMS Medizinische Informatik, Biometrie Und Epidemiologie, 19, Doc02. doi: 10.3205/mibe000241

Filter:

Trial ID Phase Status Type
Results Reported Result Refs Exist Enrollment From To
Free Text
Annotations

7805 Trials matched filter criteria

Status:   Withdrawn   Suspended   Terminated
Trial Updated /
Type
Status Phase Were
Results
Reported
Reported
Actual
Enrollment
(MeSH) Terms Why Stopped
Limitations And Caveats
Annotator decisions
NCT01205217
Details
2017-06-07
Interventional
20 
Cyclophosphamid… Epirubicin Lapatinib Paclitaxel Trastuzumab
Breast Neoplasm… Neoplasms, Brea…
Data presented at SABCS 2010 showing that dual blockade is superior to monotherapy
-
NCT01166724
Details
2017-06-07
Interventional
312 
Sirolimus Tacrolimus
Kidney Transpla…
Collaborator stopped study
Early termination; Sponsor discontinued the study for corporate reasons. No data analyzed.
NCT00632203
Details
2017-06-07
Interventional
2
[1 Refs]
53 
Temozolomide
Carcinoma Carcinoma, Larg… Carcinoma, Non-… Carcinoma, Squa… Adenocarcinoma
-
The interpretation of the study results should be taken with caution because of the small sample size due to early termination.
NCT00604968
Details
2017-06-07
Interventional
4
[1 Refs]
25 
Doxorubicin Liposomal doxor…
Breast Neoplasm…
-
-
NCT02125643
Details
2017-06-05
Interventional
1
[7 Refs]
3 
Caffeine
Healthy
Protocol was deem insufficient to answer research question
-
NCT01972516
Details
2017-06-05
Interventional
24 
Tivozanib
Fallopian Tube … Ovarian Neoplas… Fallopian Tube … Ovarian Cancer Primary Periton…
due to slow accrual
Terminated early due to low accrual.
NCT00637494
Details
2017-06-05
Interventional
3292 
Mifepristone
Depression Depressive Diso… Depressive Diso… Mental Disorder… Psychotic Disor… Psychosis Psychotic Depre… Severe Major De…
DRC recommended stopping study as it had missed its primary endpoint
-
NCT01019707
Details
2017-06-02
Interventional
16 
Atomoxetine Hyd…
Methamphetamine… Methamphetamine…
End in funding
Early termination leading to small number of subject analyzed
NCT01712399
Details
2017-06-01
Interventional
2409 
Mavrilimumab
Arthritis Arthritis, Rheu… Rheumatoid Arth…
The study was terminated after approximately 3 years due to future clinical development plans, including ethical considerations.
The study was terminated after approximately 3 years due to future clinical development plans, including ethical considerations.
NCT00986947
Details
2017-06-01
Interventional
220 
Rituximab
Renal Insuffici… Kidney Failure
-
-
NCT00787787
Details
2017-06-01
Interventional
241 
Capecitabine Sunitinib
Carcinoma Carcinoma, Hepa… Liver Neoplasms Adult Primary H… Advanced Adult … Localized Unres… Recurrent Adult…
-
-
NCT00708721
Details
2017-06-01
Interventional
1/211 
Clofarabine
Leukemia Leukemia, Myelo… Leukemia, Myelo… Leukemia, Myelo… Myelodysplastic… Preleukemia Cancer Chronic Myelomo…
Data analysis revealed sufficient data for safety and efficacy
-
NCT00673153
Details
2017-06-01
Interventional
231 
Calicheamicins Gemtuzumab Vorinostat
Leukemia Leukemia, Eryth… Leukemia, Megak… Leukemia, Monoc… Leukemia, Myelo… Leukemia, Myelo… Leukemia, Myelo… Adult Acute Meg… Adult Acute Min… Adult Acute Mon… Adult Acute Mon… Adult Acute Mye… Adult Acute Mye… Adult Acute Mye… Adult Acute Mye… Adult Acute Mye… Adult Acute Mye… Adult Acute Mye… Adult Acute Mye… Adult Erythrole… Adult Pure Eryt… Untreated Adult…
-
-
NCT02648633
Details
2017-05-31
Interventional
14 
Nivolumab Valproic Acid
Glioblastoma
The pharmaceutical company (BMS) would no longer provide nivolumab for the study, so the study was terminated early.
-
NCT01729338
Details
2017-05-31
Interventional
217 
Bortezomib Cyclophosphamid… Lenalidomide
Multiple Myelom… Neoplasms, Plas…
-
-
NCT01310855
2010-021531-13
Details
2017-05-31
Interventional
238 
Cediranib Gefitinib
Glioblastoma
closed to recruitment early due to AstraZeneca not developing cediranib further
-
NCT01201213
Details
2017-05-31
Interventional
414 
Anesthetics Anesthetics, Lo…
Pain
Audit pre regulatory inspection
-
NCT02856568
Details
2017-05-30
Interventional
10 
Cisplatin Gemcitabine Ricolinostat
Bile Duct Neopl… Carcinoma, Duct… Cholangiocarcin… Klatskin Tumor Non-Resectable … Recurrent Chola… Stage III Extra… Stage III Intra… Stage IIIA Hila… Stage IIIB Hila… Stage IVA Extra… Stage IVA Hilar… Stage IVA Intra… Stage IVB Extra… Stage IVB Hilar… Stage IVB Intra… Unresectable Ex…
Site dropped study
-
NCT02538081
Details
2017-05-30
Interventional
1/20 
Risperidone
Schizophrenia
Withdrawn
-
NCT02259348
Details
2017-05-30
Interventional
212 
Aldesleukin Cyclophosphamid… Fludarabine Fludarabine pho… Interleukin-2 Mechlorethamine Melphalan Rituximab Thiotepa
Hematologic Neo… Leukemia Leukemia, Myelo… Leukemia, Myelo… Leukemia, Myelo… Leukemia, Myelo… Lymphoma, Non-H… Myelodysplastic… Neoplasms Precursor Cell … Preleukemia Sarcoma, Myeloi… Acute Lymphobla… Acute Myeloid L… Chronic Myeloge… Juvenile Myelom… Myelodysplastic… Myeloid Sarcoma Non-Hodgkin Lym…
Investigator's decision.
The trial was terminated early due to investigator's decision.