Friedrichs, M. (2023). A web-based annotation tool for clinical trial failure reasons. GMS Medizinische Informatik, Biometrie Und Epidemiologie, 19, Doc02. doi: 10.3205/mibe000241

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Trial ID Phase Status Type
Results Reported Result Refs Exist Enrollment From To
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7805 Trials matched filter criteria

Status:   Withdrawn   Suspended   Terminated
Trial Updated /
Type
Status Phase Were
Results
Reported
Reported
Actual
Enrollment
(MeSH) Terms Why Stopped
Limitations And Caveats
Annotator decisions
NCT02562417
Details
2017-07-21
Interventional
40 
Dexamethasone
Neuromuscular B…
Change of practice in the department
-
NCT02210104
Details
2017-07-21
Interventional
10 
Cyclophosphamid… Ipilimumab
Melanoma Sarcoma
Issues with tetramer staining
-
NCT01994967
Details
2017-07-21
Interventional
30 
Bupivacaine Levobupivacaine
Musculoskeletal… Spinal Diseases Orthopedic Diso…
Another regulatory way was defined.
-
NCT01067066
Details
2017-07-21
Interventional
121 
Temozolomide
Melanoma
Phase I/II study halted as Phase I, Low Response Rate
-
NCT01038739
2009-015158-39
Details
2017-07-21
Interventional
3
[3 Refs]
330 
Mesalamine
Diverticulitis Recurrence
Stopped due to futility.
-
NCT00384865
Details
2017-07-21
Interventional
2
[1 Refs]
64 
Aspirin Simvastatin
Hypertension Hypertension, P… Pulmonary Arter…
-
The primary end point that should be used in early-stage clinical trials in PAH is uncertain. We did not include invasive hemodynamic end points. Early termination led to missing data for those active subjects in the trial at termination (n16).
NCT02227368
Details
2017-07-19
Interventional
240 
Ticagrelor
Peripheral Arte… Peripheral Arte…
-
This study was terminated early for low enrolment. Less than 25% of anticipated number of subjects were enroled and there was an imbanlance between groups. Therefore, the results should be interpreted with caution.
NCT01550302
Details
2017-07-18
Interventional
410 
Bupivacaine
Shoulder Pain
Unable to continue enrollment due to lack of resources (research coordinator no longer available).
-
NCT01459796
Details
2017-07-18
Interventional
3220 
Allopurinol Rilonacept
Gout
-
-
NCT01526876
Details
2017-07-17
Interventional
40 
Clevidipine
Hypertension
Terminated by Sponsor
-
NCT00041470
Details
2017-07-17
Interventional
1/238 
Paclitaxel Trastuzumab Vinorelbine
Breast Neoplasm… Breast Cancer
Sponsor withdrew the study
-
NCT03193359
Details
2017-07-14
Interventional
30 
Botulinum Toxin… Botulinum Toxin… abobotulinumtox…
Headache Migraine Disord…
Corporate Decision
-
NCT03193346
Details
2017-07-14
Interventional
30 
Botulinum Toxin… Botulinum Toxin… abobotulinumtox…
Headache Migraine Disord…
Corporation Decision
-
NCT00811174
Details
2017-07-14
Interventional
35 
Immunoglobulins… Rho(D) Immune G… gamma-Globulins
Immunologic Def… Primary Immunod…
Due to limited data available, efficacy, and PK analyses were not performed.
-
NCT02633384
Details
2017-07-13
Interventional
4
[8 Refs]
52 
SMOFlipid Sorbitol
Cholestasis Intrahepatic, C…
One of the intravenous lipid emulsions was retired from the market
-
NCT02623478
2015-003353-18
Details
2017-07-13
Interventional
10 
Insulin Lispro
Diabetes Mellit… Diabetes Mellit…
Change in clinical strategy
-
NCT02623465
2015-003353-18
Details
2017-07-13
Interventional
10 
Insulin Lispro
Diabetes Mellit… Diabetes Mellit…
Change in clinical strategy
-
NCT02623452
2015-003351-21
Details
2017-07-13
Interventional
10 
Insulin Lispro
Diabetes Mellit… Diabetes Mellit…
Change in clinical strategy
-
NCT01309126
Details
2017-07-13
Interventional
3217 
Cetuximab
Colorectal Neop… Colorectal Canc…
Due to enrollment challenges resulting from changing treatment patterns in the use of cetuximab, the study has been terminated. No patients remain on study.
-
NCT03192969
2016-002697-12
Details
2017-07-12
Interventional
30 
Abatacept Glucocorticoids
Arteritis Giant Cell Arte… Polymyalgia Rhe…
Business objectives have changed
-