Friedrichs, M. (2023). A web-based annotation tool for clinical trial failure reasons. GMS Medizinische Informatik, Biometrie Und Epidemiologie, 19, Doc02. doi: 10.3205/mibe000241

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Trial ID Phase Status Type
Results Reported Result Refs Exist Enrollment From To
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7805 Trials matched filter criteria

Status:   Withdrawn   Suspended   Terminated
Trial Updated /
Type
Status Phase Were
Results
Reported
Reported
Actual
Enrollment
(MeSH) Terms Why Stopped
Limitations And Caveats
Annotator decisions
NCT02279342
Details
2017-08-03
Interventional
41 
Febuxostat
Angina, Stable Coronary Artery… Coronary Diseas… Hyperuricemia Myocardial Isch…
Entry were insufficient as expected.
-
NCT02429076
Details
2017-08-02
Interventional
1/20 
Methylphenidate Propofol Sevoflurane
Active Emergenc…
We are not going to complete this study with healthy volunteers at this time.
-
NCT02316496
Details
2017-08-01
Interventional
22 
Cetuximab Irinotecan
Colorectal Neop… Colorectal Canc…
-
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NCT00386516
Details
2017-08-01
Interventional
20 
Fluorouracil
Bile Duct Neopl… Gallbladder Neo… Cancer of the B… Gallbladder Can…
Financing and re-organization
-
NCT00381810
Details
2017-08-01
Interventional
331 
Acetaminophen Diphenhydramine Methylprednisol… Promethazine Rituximab
Lupus Erythemat…
During a safety review of studies U2970g and U2971g, the Data Monitoring Committee recommended that enrollment in this extension trial be terminated.
Since study U2971g did not demonstrate efficacy, a decision was made not to evaluate efficacy in this study and only safety results were evaluated.
NCT00089778
NCT00091403
Details
2017-08-01
Interventional
211 
Aldesleukin Interleukin-2 Mitogens
Carcinoma, Rena… Kidney Neoplasm… Kidney Cancer
fewer tumors than expected expressed FGF-5, led to end of accrual to cohorts A&B
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NCT02442674
Details
2017-07-31
Interventional
30 
Tolvaptan
Hyponatremia
Trial withdrawn due to inability to meet the trial objectives (Pilot).
-
NCT02674555
Details
2017-07-28
Interventional
10 
Naquotinib
Neoplasms Epidermal Growt… Solid Tumors
Following recommendation by SOLAR Study IDMC, Astellas closed enrollment in ASP8273 studies.
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NCT01856517
Details
2017-07-28
Interventional
2/3-
Clonidine
Shock Shock, Septic Septic Shock
-
-
NCT02651727
Details
2017-07-27
Interventional
113 
Albumin-Bound P… Gemcitabine Paclitaxel
Pancreatic Canc…
the company's decision to de-prioritize 4718 development
-
NCT01764997
2012-001984-66
Details
2017-07-27
Interventional
3776 
Adalimumab Etanercept Methotrexate
Arthritis Arthritis, Rheu… Rheumatoid Arth…
Due to small number of participants entering randomization. Not a safety issue.
The study was prematurely terminated due to small number of participants entering randomization.
NCT02563782
Details
2017-07-26
Interventional
20 
Mycophenolic Ac… Tacrolimus
Macular Degener… Age-Related Mac…
Changes to the study design and the cell line
-
NCT01260103
Details
2017-07-26
Interventional
30 
Temozolomide
Glioma Optic Nerve Gli…
Withdrawn: study halted prematurely, prior to enrollment of first participant
-
NCT00590135
Details
2017-07-26
Interventional
459 
Atorvastatin
Aortic Valve St… Constriction, P…
Poor Reducibility - primary endpoint measure not obtainable
-
NCT03216876
Details
2017-07-25
Interventional
10 
Ursolic Acid
Cholangitis Cholangitis, Sc… Primary Scleros…
Lack of feasibility
-
NCT02191748
Details
2017-07-25
Interventional
2/322 
Triamcinolone
Vitiligo
Principal investigator made the decision to close study and not submit a renewal. Lack of fixed research personnel to carry out the study effectively.
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NCT00695643
2007-000680-22
Details
2017-07-24
Interventional
3
[3 Refs]
345 
Mesalamine
Diverticulitis Recurrence
-
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NCT03137030
Details
2017-07-21
Interventional
10 
Acetaminophen Hydrocodone
Acute Pain Opioid-Related … Pain, Postopera… Pain, Acute
program discontinued
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NCT03137017
Details
2017-07-21
Interventional
10 
Acetaminophen Hydrocodone
Acute Pain Opioid-Related … Pain, Postopera… Pain, Acute
program discontinued
-
NCT02732327
Details
2017-07-21
Interventional
22 
Cefepime Linezolid Meropenem Piperacillin Piperacillin, T… Tazobactam Vancomycin
Febrile Neutrop… Fever Hyperthermia Neutropenia Neoplasms
No longer aligned with the revised clinical development plan and commercial strategy
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