Friedrichs, M. (2023). A web-based annotation tool for clinical trial failure reasons. GMS Medizinische Informatik, Biometrie Und Epidemiologie, 19, Doc02. doi: 10.3205/mibe000241

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Results Reported Result Refs Exist Enrollment From To
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7805 Trials matched filter criteria

Status:   Withdrawn   Suspended   Terminated
Trial Updated /
Type
Status Phase Were
Results
Reported
Reported
Actual
Enrollment
(MeSH) Terms Why Stopped
Limitations And Caveats
Annotator decisions
NCT03143998
Details
2017-11-09
Interventional
40 
Elbasvir-grazop… Grazoprevir
Hepatitis Hepatitis A Hepatitis C Hepatitis C, Ch…
Business reasons
-
NCT02840591
Details
2017-11-09
Interventional
40 
Cytidine Diphos…
Delirium
Stopped the study due to feasibility issues, no enrollment has taken place.
-
NCT02936492
Details
2017-11-08
Interventional
132 
Clobetasol
Psoriasis
-
-
NCT02510248
Details
2017-11-08
Interventional
142 
1-2-isopropoxy-…
Hepatitis C Hepatitis C, Ch… Chronic Hepatit…
-
-
NCT01005459
Details
2017-11-08
Interventional
446 
Bupivacaine Tetracaine
Labor Pain
feasibility /drug availability issues - No study drug sources available
-
NCT00550420
Details
2017-11-08
Interventional
3331 
Rosiglitazone
Alzheimer Disea… Alzheimer's Dis…
Based on preliminary parent study results
The study was early terminated on 12 February 2009 because RSG XR as monotherapy in Alzheimer's disease failed to demonstrate efficacy.
NCT03024060
Details
2017-11-07
Interventional
30 
Aminolevulinic …
Keratosis Keratosis, Acti… Actinic Keratos…
Study withdrawn due to corporate business decision
-
NCT00471237
Details
2017-11-07
Interventional
2564 
Alendronate Teriparatide
Osteoporosis
Terminated for futility by sponsor after a pre-planned interim review of data
The study was terminated for futility in a phased manner by the sponsor on 25-Sep-2008 once the results of a planned 6-month interim analysis were available.
NCT03219983
Details
2017-11-06
Interventional
422 
Bupivacaine Ropivacaine
Arthritis Glenohumeral Ar… Total Shoulder …
-
-
NCT02642523
Details
2017-11-06
Interventional
10 
Insulin Insulin, Globin… Natriuretic Pep…
Hyperinsulinism Obesity Hyperinsulinemi…
Preliminary data run on rat samples showed that this study question and design would not produce conclusive results. The PI decided not to carry out the study.
-
NCT02221947
Details
2017-11-06
Interventional
1/29 
Bryostatin 1
Alzheimer Disea… Alzheimer's Dis…
Part 2 of study replaced by NTRP-101-202, assessing 3 doses of bryostatin.
-
NCT01362205
Details
2017-11-06
Interventional
449 
Dexmedetomidine
Alcohol Withdra… Delirium Substance Withd… Alcohol Withdra… Alcohol Withdra… Alcohol Withdra…
DSMB recommendation for slow enrollment
Early termination due to slow enrollment leading to small numbers of subjects analyzed
NCT00690911
Details
2017-11-06
Interventional
20 
Adalimumab
Sarcoidosis
Dr. Jorizzo has decided to withdraw from this study due to the time it is taking to get the study started.
-
NCT00611455
Details
2017-11-06
Interventional
3265 
Ofatumumab
Arthritis Arthritis, Rheu…
Ofatumumab IV trials in RA were prematurely terminated because GSK refocused clinical development of autoimmune indications on the subcutaneous delivery.
-
NCT00400205
Details
2017-11-06
Interventional
2
[1 Refs]
14 
Docetaxel Fluorouracil
Carcinoma Carcinoma, Squa… Mouth Neoplasms Oral Cancer Squamous Cell C…
Safety reasons
-
NCT03095547
Details
2017-11-01
Interventional
10 
Cyclosporine Cyclosporins Olorofim Pantoprazole Posaconazole Tacrolimus
Aspergillosis Invasive Asperg…
study no longer required in current format
-
NCT03076905
Details
2017-11-01
Interventional
10 
Olorofim
Aspergillosis Invasive Asperg…
study no longer required in current format
-
NCT02999906
Details
2017-11-01
Interventional
30 
Treprostinil
Familial Primar… Hypertension Pulmonary Arter…
For business reasons.
-
NCT02433483
Details
2017-11-01
Interventional
24 
Cytarabine Hydrocortisone Methotrexate
Hematologic Neo… Leukemia, Myelo… Myelodysplastic… Preleukemia Acute Myeloid L… Myelodysplastic…
The study was closed due to poor accrual and because of competing protocols.
This study was terminated in May 2017 due to poor accrual and because of competing protocols.
NCT01666600
Details
2017-11-01
Interventional
1/263 
Nintedanib
Glioblastoma Glioblastoma Mu…
Interim Analysis for Feasibility
-