Friedrichs, M. (2023). A web-based annotation tool for clinical trial failure reasons. GMS Medizinische Informatik, Biometrie Und Epidemiologie, 19, Doc02. doi: 10.3205/mibe000241

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7805 Trials matched filter criteria

Status:   Withdrawn   Suspended   Terminated
Trial Updated /
Type
Status Phase Were
Results
Reported
Reported
Actual
Enrollment
(MeSH) Terms Why Stopped
Limitations And Caveats
Annotator decisions
NCT01281254
2009-017946-30
Details
2017-12-02
Interventional
3223 
Trebananib
Carcinoma, Ovar… Fallopian Tube … Ovarian Neoplas… Fallopian Tube … Ovarian Cancer Primary Periton…
Closure of long term follow up (LTFU) and study earlier than previously outlined in the protocol as no beneficial information gained from continuing LTFU.
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NCT01190722
Details
2017-12-02
Interventional
40 
Diclofenac Etoricoxib
Bunion Hallux Valgus Pain, Postopera… Postoperative P…
The study site was closed down
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NCT01163201
Details
2017-12-02
Interventional
1/20 
Cyclophosphamid… Fludarabine
Anemia, Refract… Anemia, Refract… Blast Crisis Burkitt Lymphom… Hematologic Neo… Leukemia Leukemia, Lymph… Leukemia, Lymph… Leukemia, Myelo… Leukemia, Myelo… Lymphoma Lymphoma, B-Cel… Lymphoma, Mantl… Lymphoma, Non-H… Myeloproliferat… Neoplasms Precursor Cell … Waldenstrom Mac… Acute Lymphocyt… Acute Myeloid L… Anemia, Refract… Burkitt's Lymph… Chronic Lymphoc… Chronic Myeloge… Chronic Myelopr… Follicular Lymp… Hematologic Mal… High Grade Non-… Large Cell Non-… Lymphoblastic L… Lymphoplasmacyt… Mantle-Cell Lym… Marginal Zone B… Prolymphocytic … Small Lymphocyt…
Replaced by a new study
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NCT00664209
Details
2017-12-02
Interventional
364 
Amoxicillin Omeprazole
Helicobacter In… Parkinson Disea… Motor Fluctuati… Parkinson's Dis…
Prevalence of H Pylori in the study population was much lower than anticipated
Screening yield was much lower than anticipated based on the literature which prohibited completion of the study
NCT00314613
Details
2017-12-02
Interventional
4-
Antipsychotic A… Risperidone
Schizophrenia
-
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NCT02947113
2016-003790-18
Details
2017-11-30
Interventional
20 
Etoposide Pemetrexed
Carcinoma, Non-… Non-Small Cell …
New studies available with immunotherapy so recruitment is no longer acceptable.
-
NCT01381562
Details
2017-11-29
Interventional
215 
Meropenem
Communicable Di… Infections Intraabdominal … Infections, Int…
Microbiological findings of resistance on therapy in patients with complicated urinary tract infection
This study was terminated early because only 15 participants were enrolled.
NCT00702793
Details
2017-11-29
Interventional
40 
Varenicline
Mental Disorder… Psychotic Disor… Schizophrenia Psychosis Schizoaffective
No participants enrolled
-
NCT00618696
Details
2017-11-29
Interventional
14 
Antibodies Antibodies, Mon… Antineoplastic … Immunoglobulins
Leukemia Myelodysplastic… Preleukemia
Replaced with another study
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NCT00005993
Details
2017-11-29
Interventional
1-
Aldesleukin
Breast Neoplasm… Lymphoma Breast Cancer
-
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NCT00929669
Details
2017-11-28
Interventional
22 
Pasireotide
Adenoma Gonadotroph Ade…
unable to identify a third subject
This trial was terminated due to difficulty in identifying 3 subjects for completion of the study.
NCT00119184
Details
2017-11-28
Interventional
1140 
Anesthetics
Breech Presenta…
Multiparas study terminated due to poor recruitment. Randomization revealed only after decision recorded on clinicaltrials.gov
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NCT02299765
Details
2017-11-27
Interventional
461 
Carboplatin Gefitinib Gemcitabine
Carcinoma, Non-… EGFR Activating… Non-small Cell …
the research data is not statistically significant
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NCT02176122
Details
2017-11-27
Interventional
4391 
Meropenem Piperacillin Piperacillin, T… Tazobactam
Infections Sepsis Bloodstream Inf…
Secondary to third interim analysis by the study DSMB.
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NCT02912169
Details
2017-11-24
Interventional
1/20 
Anesthetics
Alzheimer Disea… Alzheimer's Dis…
company dissolved
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NCT02719015
Details
2017-11-24
Interventional
1/20 
Pembrolizumab
Melanoma
No IND Serial #
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NCT01969565
Details
2017-11-24
Interventional
21 
Dexamethasone
Multiple Myelom… Neoplasms, Plas…
Logistical reasons
One patient consented but withdrew prior to beginning treatment.
NCT01559051
Details
2017-11-24
Interventional
1/20 
Anesthetics
Lung Diseases Lung Diseases, … Pulmonary Disea… Chronic Obstruc…
company dissolved
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NCT02847702
Details
2017-11-22
Interventional
275 
Naproxen
Osteoarthritis Osteoarthritis …
Company decision
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NCT02122003
Details
2017-11-22
Interventional
216 
Sorafenib
Carcinoma Carcinoma, Rena… Metastatic Rena…
availability of new and more promising therapeutic agents than expected in the experimentation in question
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