Friedrichs, M. (2023). A web-based annotation tool for clinical trial failure reasons. GMS Medizinische Informatik, Biometrie Und Epidemiologie, 19, Doc02. doi: 10.3205/mibe000241

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Trial ID Phase Status Type
Results Reported Result Refs Exist Enrollment From To
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7805 Trials matched filter criteria

Status:   Withdrawn   Suspended   Terminated
Trial Updated /
Type
Status Phase Were
Results
Reported
Reported
Actual
Enrollment
(MeSH) Terms Why Stopped
Limitations And Caveats
Annotator decisions
NCT02157272
2013-004575-13
Details
2018-01-30
Interventional
3121 
Rivaroxaban
Antiphospholipi… Syndrome
Unbalance in the composite endpoint between arms.
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NCT01682512
2011-002894-48
Details
2018-01-30
Interventional
3294 
Rituximab
Arthritis Arthritis, Rheu…
substance discontinued
The study program was terminated and this study was discontinued on 3 September 2015. As a result no patients receiving study treatment in Part II of the study reached Week 24, and no conclusions regarding the efficacy of BI 695500 can be made.
NCT03363191
Details
2018-01-29
Interventional
40 
Albuterol Fluticasone Xhance
Asthma
The study was withdrawn due to an internal decision.
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NCT02609048
Details
2018-01-29
Interventional
241 
Seladelpar
Fibrosis Liver Cirrhosis Liver Cirrhosis… Primary Biliary…
Study stopped early after review of safety and efficacy demonstrated efficacy proof-of-concept and need for dose reduction.
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NCT02221674
2014-000623-24
Details
2018-01-29
Interventional
240 
Tapentadol
Pain, Postopera… Moderate to Sev…
-
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NCT02780882
Details
2018-01-26
Interventional
20 
Pasireotide
ACTH Syndrome, … Cardiac Complex… Cushing Syndrom… Ectopic ACTH Sy…
Due to stringent inclusion/exclusion criteria, study investigator deemed it not feasible.
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NCT02539810
Details
2018-01-26
Interventional
44 
Antihypertensiv…
Constriction, P… Hypertension Renal Artery Ob… Angiographicall… Hypertension Re…
-
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NCT00311558
Details
2018-01-26
Interventional
118 
Antimony Sodium… Interferon alph… Interferon-alph… Interferons
Lymphoma Cancer
-
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NCT02975583
Details
2018-01-25
Interventional
40 
Vorapaxar
Peripheral Arte… Peripheral Arte…
We could not secure adequate medication
-
NCT02257619
Details
2018-01-25
Interventional
29 
Docetaxel
Carcinoma, Non-… Lung Neoplasms NSCLC (Non-smal…
Sponsor decision to not initiate part 2 due to slow enrollment and competing trials.
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NCT01759407
Details
2018-01-25
Interventional
219 
Epinephrine
Femoral Fractur… Fractures, Bone Traumatic Femur…
Interim analysis showed no significant difference between study arms.
-
NCT01631513
Details
2018-01-25
Interventional
40 
Tapentadol
Back Pain Low Back Pain Osteoarthritis Chronic Back Pa… Chronic Low Bac… Osteoarthritis … Pain
It was a business decision to cancel this study in Aug. 2012.
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NCT02578719
Details
2018-01-23
Interventional
40 
Bupivacaine
Migraine Disord…
Local Drug Authority didn't give permission to start.
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NCT02176642
Details
2018-01-23
Interventional
455 
Oxybutynin
Urinary Inconti… Urinary Urge In…
-
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NCT02134015
2013-004371-12
Details
2018-01-23
Interventional
3145 
Erlotinib Hydro…
Carcinoma, Non-… Lung Neoplasms Lung Cancer Non-small Cell …
Pre-defined criteria for continuation were not reached
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NCT01655992
Details
2018-01-23
Interventional
3-
Capecitabine Tegafur
Breast Neoplasm… Metastatic Brea…
The sponsor decided to stop the study.
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NCT01469988
Details
2018-01-23
Interventional
2-
Testosterone
Heart Failure
Feasibility
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NCT01035801
Details
2018-01-23
Interventional
120 
Insulin Lispro
Diabetes Mellit… Diabetes Mellit… Type 1 Diabetes…
This study was temporarily paused due to an unanticipated bioanalytical issue.
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NCT00522548
Details
2018-01-23
Interventional
437 
Mycophenolic Ac…
Transplants and…
enrollment halted in order to have all patients complete follow-up by Jan 2011
Limitations of our study include small sample size and patient drop out-though not significantly different between the MMF and EC-MPS groups and limited follow-up
NCT00176826
NCT00973843
Details
2018-01-23
Interventional
2/322 
Busulfan
Chediak-Higashi… Hematologic Dis… Histiocytosis Histiocytosis, … Immune System D… Immunologic Def… Lymphohistiocyt… Lymphoprolifera… Syndrome Griscelli Syndr… Hemophagocytic … Immunologic Dis… Langerhans-Cell… X-Linked Lympho…
Replaced by another protocol
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