Friedrichs, M. (2023). A web-based annotation tool for clinical trial failure reasons. GMS Medizinische Informatik, Biometrie Und Epidemiologie, 19, Doc02. doi: 10.3205/mibe000241

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Trial ID Phase Status Type
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7805 Trials matched filter criteria

Status:   Withdrawn   Suspended   Terminated
Trial Updated /
Type
Status Phase Were
Results
Reported
Reported
Actual
Enrollment
(MeSH) Terms Why Stopped
Limitations And Caveats
Annotator decisions
NCT01813253
Details
2018-03-26
Interventional
3400 
Irinotecan Nimotuzumab
Stomach Neoplas… Gastric Cancer Gastroesophagea…
-
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NCT03054948
Details
2018-03-22
Interventional
40 
SMOFlipid
Short Bowel Syn… Home Parenteral…
Redesign of study protocol.
-
NCT02269696
Details
2018-03-22
Interventional
30 
Metoprolol
Breast Neoplasm… Mastodynia Breast Cancer
Withdrawn
-
NCT01123915
2008-005142-23
Details
2018-03-22
Interventional
122 
Dimethyl Sulfox…
HIV Infections
-
-
NCT01511263
Details
2018-03-21
Interventional
286 
Amiodarone Anti-Arrhythmia… Diuretics
Amyloidosis Immunoglobulin … Primary Amyloid…
-
-
NCT00273026
Details
2018-03-21
Interventional
4-
Fluticasone Salmeterol Xina… Xhance
Asthma
-
-
NCT01271010
Details
2018-03-20
Interventional
489 
Cyclophosphamid… Fludarabine Rituximab
Leukemia Leukemia, Lymph… Leukemia, Lymph… Lymphocytic Leu…
-
-
NCT00623415
2006-005262-39
Details
2018-03-20
Interventional
230 
Flupirtine
Multiple Sclero… Multiple Sclero… Sclerosis Relapsing Remit…
-
-
NCT01543464
Details
2018-03-19
Interventional
241 
Temozolomide
Melanoma Malignant Melan…
Diminished rectruitment
-
NCT03235869
Details
2018-03-15
Interventional
10 
Durvalumab
Lymphoma Lymphoma, T-Cel… Lymphoma, T-Cel… Lymphoma, T-Cel… Cutaneous T Cel…
The company pulled durvalumab from heme malignancies
-
NCT03073369
Details
2018-03-15
Interventional
40 
Ergocalciferols Vitamin D
Iron Deficienci… Kidney Diseases Renal Insuffici… Anemia CKD Chronic Kidney … Ergocalciferol Hepcidin Iron-deficiency Vitamin D
Study didn't materialize for various reasons.
-
NCT02469311
Details
2018-03-14
Interventional
2539 
Anti-Bacterial … Chlorhexidine
Infections Infection Osteoarthritis
Preliminary results showed that the use of the cloths helped prevent infections.
-
NCT00354107
Details
2018-03-14
Interventional
1/25 
Antibodies Antibodies, Mon… Brentuximab Ved… Carboplatin Cytarabine Etoposide Etoposide phosp… Hydrocortisone Hydrocortisone … Hydrocortisone … Hydrocortisone … Ifosfamide Methotrexate
Lymphoma Lymphoma, Large… Lymphoma, Non-H… Recurrence Anaplastic Larg… Recurrent Child…
-
Number of participants analyzed = 4. One patient was not evaluable for response. The Secondary Outcome measures will never be reported as data were not collected to assess these study aims.
NCT00169026
Details
2018-03-14
Interventional
4-
Antipsychotic A… Clozapine
Alcoholism Psychotic Disor… Schizophrenia Substance-Relat… Alcohol Abuse Dual Diagnosis Psychotic Disor… Schizoaffective… Substance Abuse
-
-
NCT01866943
Details
2018-03-13
Interventional
241 
Tranexamic Acid
Hemorrhage Postoperative H… Post Operative …
-
The study team is limited by a change in personnel. The data is not available classified by group: the only spreadsheet is incomplete, blinded and de-identified. The previous personnel have been contacted and are not cooperative.
NCT00705796
Details
2018-03-13
Interventional
10 
Methyltestoster… Testosterone Testosterone 17… Testosterone en… Testosterone un…
Hypogonadism
financial constraints
-
NCT02730364
Details
2018-03-12
Interventional
30 
Acetaminophen Oxymetazoline Pheniramine Phenylephrine
Infections Respiratory Tra… Infections, Res…
The clinical phase of the study (from FSFV to LSLV) was never initiated due to the sponsor's decision.
-
NCT02678234
Details
2018-03-12
Interventional
30 
Acetaminophen Oxymetazoline Phenylephrine
Infections Respiratory Tra… Infections, Res…
The clinical phase of the study (from FSFV to LSLV) was never initiated due to the sponsor's decision.
-
NCT02366663
Details
2018-03-12
Interventional
33 
Carmustine Cytarabine Etoposide Melphalan Rituximab
Lymphoma Lymphoma, B-Cel… Lymphoma, Large… Recurrent Diffu… Refractory Diff…
Withdrawal of sponsor support
-
NCT01188408
Details
2018-03-12
Interventional
20 
Docetaxel
Prostatic Neopl… Prostate Cancer
Study shut-down in 12/2010 when NeoPharm merged with Insys.
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