Friedrichs, M. (2023). A web-based annotation tool for clinical trial failure reasons. GMS Medizinische Informatik, Biometrie Und Epidemiologie, 19, Doc02. doi: 10.3205/mibe000241

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Trial ID Phase Status Type
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7805 Trials matched filter criteria

Status:   Withdrawn   Suspended   Terminated
Trial Updated /
Type
Status Phase Were
Results
Reported
Reported
Actual
Enrollment
(MeSH) Terms Why Stopped
Limitations And Caveats
Annotator decisions
NCT02708511
Details
2018-04-05
Interventional
12 
Copper
Breast Neoplasm… Carcinoma Breast Carcinom… Ovarian Carcino…
-
-
NCT02374489
Details
2018-04-05
Interventional
29 
Ceritinib
Cholangiocarcin… Klatskin Tumor
ROS1 in IHC and gene rearrangement result can not match。No tumor response。
-
NCT02197182
Details
2018-04-05
Interventional
150 
Copper Metronidazole
Vaginal Disease… Vaginosis, Bact… Bacterial Vagin…
Not for safety reasons
-
NCT01702896
Details
2018-04-05
Interventional
28 
Interleukin-2
Melanoma Melanoma Metast…
PI Decision
-
NCT03307993
Details
2018-04-04
Interventional
13 
(2-(6-fluoro-1H…
Alzheimer Disea… Alzheimer's Dis…
The study was terminated for strategic reasons.
-
NCT02048085
Details
2018-04-04
Interventional
40 
Clopidogrel Ticagrelor
Acute Coronary … Infarction Myocardial Infa… ST Elevation My… Acute ST Segmen…
unable to get study up and enrolling
-
NCT01702792
Details
2018-04-04
Interventional
11 
Monatide (IMS 3…
Glioblastoma
Investigator is leaving Dartmouth
-
NCT01692691
Details
2018-04-04
Interventional
21 
Carmustine Dacarbazine
Melanoma Melanoma Metast…
PI decision
-
NCT00961571
Details
2018-04-03
Interventional
250 
Capecitabine Sunitinib
Colorectal Neop… Metastatic Colo…
Unanticipated side effects and futility
-
NCT00421720
2006-001276-20
Details
2018-04-03
Interventional
4-
Remifentanil Sufentanil
Agnosia Analgesia Sedation
-
-
NCT00997581
Details
2018-04-02
Interventional
20 
Apremilast Indomethacin
Arthritis, Gout… Acute Gout
Colaborator withdrew support.
-
NCT03303677
Details
2018-03-30
Interventional
3
[12 Refs]
0 
Anti-Bacterial … Budesonide Ciprofloxacin Gentamicins Mupirocin Sulfamethoxazol… Trimethoprim Vancomycin
Rhinosinusitis Chronic Rhinosi…
Withdrawn by sponsor
-
NCT01676415
Details
2018-03-30
Interventional
49 
Glucocorticoids Mometasone Furo… Prednisone
Nasal Polyps Polyps Rhinosinusitis Sinusitis Chronic Rhinosi…
participants are no longer receiving intervention due to clinical logistics
Study had difficult accruing sufficient numbers of patients. Additional Institutional Review Board mandated testing for potential participants made study flow challenging. Study was closed for failure to accrue sufficient patients.
NCT00857597
Details
2018-03-30
Interventional
360 
Esomeprazole Omeprazole Pantoprazole Proton Pump Inh… Rabeprazole
Gastroesophagea… Gastroesophagea…
Study was terminated after unplanned interim analysis of single centre data and results were reported
-
NCT01921985
Details
2018-03-29
Interventional
2150 
Terlipressin
Liver Failure Liver Resection
Interim analysis revealed that no statistical difference will be identified after inclusion of the patient cohort as foreseen in the sample size calculation
-
NCT00642603
Details
2018-03-29
Interventional
241 
Bevacizumab Capecitabine Irinotecan Oxaliplatin
Colorectal Neop… Colorectal Canc…
-
This study was terminated early because interim data from a predecessor study invalidated the scientific rationale that provided justification for the conduct of this study. Efficacy analyses were not performed.
NCT00323635
Details
2018-03-29
Interventional
419 
Tolterodine Tar…
Enuresis Urinary Inconti…
New department chairman instructed PI to discontinue study.
-
NCT00281021
Details
2018-03-29
Interventional
226 
Digoxin Erlotinib Hydro…
Carcinoma, Non-… Lung Neoplasms Carcinoma, Non-…
Interim analysis revealed that only 1 patient had a partial response.
-
NCT03222089
Details
2018-03-27
Interventional
20 
Fluorouracil Interleukin-2 Irinotecan Leucovorin Levoleucovorin Molgramostim Oxaliplatin Sargramostim
Colorectal Neop… Metastatic Colo…
Another study enrolling the similar group of patient are ongoing
-
NCT02688465
Details
2018-03-26
Interventional
415 
Apomorphine
Parkinson Disea… Parkinson's Dis…
-
-