Friedrichs, M. (2023). A web-based annotation tool for clinical trial failure reasons. GMS Medizinische Informatik, Biometrie Und Epidemiologie, 19, Doc02. doi: 10.3205/mibe000241

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Trial ID Phase Status Type
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7805 Trials matched filter criteria

Status:   Withdrawn   Suspended   Terminated
Trial Updated /
Type
Status Phase Were
Results
Reported
Reported
Actual
Enrollment
(MeSH) Terms Why Stopped
Limitations And Caveats
Annotator decisions
NCT03048136
Details
2018-04-17
Interventional
30 
Ipilimumab Nivolumab
Carcinoma, Non-… Lung Neoplasms Non-Small Cell …
Business objective has changed
-
NCT00854581
Details
2018-04-17
Interventional
413 
Interferon alph… Interferon-alph… Interferons Peginterferon a… Valproic Acid Zidovudine
Leukemia Leukemia, T-Cel… Leukemia-Lympho… Lymphoma Precancerous Co… Precancerous/No…
Investigator Decision
-
NCT03497715
Details
2018-04-13
Interventional
16 
Ibuprofen
Healthy Subject…
On completion of part 1 it was felt that there would be no benefit in completing part 2
-
NCT02933684
Details
2018-04-13
Interventional
20 
Cycloserine
Anxiety Disorde… Phobia, Social Social Anxiety …
Unable to access components necessary to be able to run the study.
-
NCT02428062
Details
2018-04-13
Interventional
2/3-
Dopamine Ephedrine Epinephrine Norepinephrine Oxymetazoline Phenylephrine Vasoconstrictor…
Cognitive Dysfu… Postoperative C… Post-operative …
Pending Pilot study results evaluation
-
NCT00763009
Details
2018-04-13
Interventional
48 
Dipyridamole
Coronary Artery…
Limited numbers of patients qualified for trial
Trial terminated early due to poor patient enrollment. All patients responded hemodynamically. Therefore, analysis of responders vs non-responders could not be performed. Adenosine transporter was not analyzed since there was no comparator group.
NCT00227136
Details
2018-04-13
Interventional
3-
Serotonin
Carcinoid Tumor Neuroendocrine … Carcinoid Tumor…
-
-
NCT00089544
Details
2018-04-13
Interventional
223 
Dacarbazine Doxorubicin Ifosfamide Imidazole Isophosphamide … Lenograstim Liposomal doxor… Thalidomide
Sarcoma Recurrent Adult… Stage I Adult S… Stage II Adult … Stage III Adult…
-
This study closed early due to unacceptably high rate of thromboembolic events in Cohort A and due to low accrual in Cohort B. For this reason efficacy endpoints other than response to pre-operative therapy were not reported.
NCT03131700
Details
2018-04-12
Interventional
10 
Bevacizumab
Healthy
Decision of the Sponsor
-
NCT00096187
Details
2018-04-12
Interventional
2-
Pemetrexed
Gestational Tro… Trophoblastic N… Gestational Tro…
-
-
NCT00005029
Details
2018-04-12
Interventional
2
[1 Refs]
-
Topotecan
Ovarian Cancer Primary Periton…
-
-
NCT00003054
Details
2018-04-12
Interventional
2
[1 Refs]
-
Paclitaxel
Sarcoma
-
-
NCT02810483
Details
2018-04-11
Interventional
369 
Topiramate
Prader-Willi Sy… Syndrome
-
-
NCT02209155
Details
2018-04-11
Interventional
21 
Verapamil
Cluster Headach… Headache Episodic Cluste…
-
-
NCT03385395
Details
2018-04-10
Interventional
20 
Alpha 1-Antitry…
Alpha 1-Antitry…
IND has been closed.
-
NCT02155634
Details
2018-04-10
Interventional
30 
Lenalidomide
Blood Protein D… Hematologic Dis… Multiple Myelom… Neoplasms, Plas… Paraproteinemia… Neoplasms Plasma Cells Therapeutic Use…
The study was terminated due to poor feasibility and lack of interest at the participating sites.
-
NCT03241017
Details
2018-04-09
Interventional
20 
Durvalumab
Lymphoma Lymphoma, Large…
Celgene withdrew the support for this study (Durvalumab cannot be provided)
-
NCT02911480
Details
2018-04-06
Interventional
10 
Oxytocin
Healthy Women o…
Study/financial issues
-
NCT02267408
Details
2018-04-06
Interventional
1/242 
Warfarin
Hypoprothrombin… Hypoprothrombin…
Terminated by sponsor
-
NCT03061136
Details
2018-04-05
Interventional
40 
Clonazepam
Psychotic Disor… Schizophrenia Schizoaffective… Schizophrenifor…
Delays in equipment procurement prevented the start of the study in time
-