Friedrichs, M. (2023). A web-based annotation tool for clinical trial failure reasons. GMS Medizinische Informatik, Biometrie Und Epidemiologie, 19, Doc02. doi: 10.3205/mibe000241

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Trial ID Phase Status Type
Results Reported Result Refs Exist Enrollment From To
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7805 Trials matched filter criteria

Status:   Withdrawn   Suspended   Terminated
Trial Updated /
Type
Status Phase Were
Results
Reported
Reported
Actual
Enrollment
(MeSH) Terms Why Stopped
Limitations And Caveats
Annotator decisions
NCT02644473
Details
2018-05-31
Interventional
40 
Tranexamic Acid
Embolism Infarction Myocardial Infa… Pulmonary Embol… Thrombosis Venous Thrombos… Deep Vein Throm… Stroke
Study did not receive IRB approval, so did not start
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NCT00827580
Details
2018-05-30
Interventional
13 
Eniluracil
Colonic Neoplas… Hand-Foot Syndr… Breast Cancer Colon Cancer
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NCT02381548
Details
2018-05-25
Interventional
120 
Adavosertib Belinostat
Blast Crisis Leukemia Leukemia, Myelo… Leukemia, Myelo… Leukemia, Myelo… Myelodysplastic… Preleukemia Recurrence Syndrome Acute Myeloid L… Blast Phase Chr… Myelodysplastic… Previously Trea… Recurrent Adult… Recurrent Chron… Refractory Acut… Refractory Chro… Secondary Acute… Therapy-Related… Untreated Adult…
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NCT02666365
Details
2018-05-24
Interventional
40 
Cefazolin
Surgical Wound … Surgical Site I…
Investigator decided not to proceed.
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NCT02448550
Details
2018-05-24
Interventional
3250 
Bivalirudin Calcium heparin Heparin
Percutaneous Co…
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NCT03023527
Details
2018-05-23
Interventional
16 
Dexamethasone Elotuzumab Nivolumab Pomalidomide
Multiple Myelom… Neoplasms, Plas…
Safety
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NCT02057289
Details
2018-05-23
Interventional
19 
Micafungin
Bone Marrow Tra… Cancer Immunocompromis…
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NCT01522443
Details
2018-05-23
Interventional
3119 
Mitoxantrone Prednisone
Prostatic Neopl… Castration Resi… Pain Prostate Cancer
Stopped after the outcome of cabozantinib Phase 3 CRPC study XL184-307.
Enrollment was stopped before planned study population size of 246 was reached (only 119 enrolled).
NCT00212004
Details
2018-05-23
Interventional
4630 
Pioglitazone
Diabetes Mellit… Infarction Myocardial Infa…
Limited budget to continue this study
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NCT03119077
2016-003520-23
Details
2018-05-17
Interventional
132 
Itraconazole
Polycystic Ovar…
Study early terminated due to lower drug exposure
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NCT02609152
2015-000895-90
Details
2018-05-17
Interventional
30 
Esmolol
Shock Shock, Septic
logistical difficulties
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NCT01471964
Details
2018-05-17
Interventional
1/222 
Erlotinib Hydro…
Carcinoma, Non-… Lung Neoplasms Non-small Cell … Non-small Cell …
Phase I portion completed. Phase II will open pending amendment approval.
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NCT01382706
Details
2018-05-16
Interventional
215 
Docetaxel Lapatinib
Carcinoma Carcinoma, Tran… Urinary Bladder… Recurrent Bladd… Stage III Bladd… Stage IV Bladde… Transitional Ce…
Trial not progressing toward scientific goals
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NCT01200589
Details
2018-05-16
Interventional
3438 
Antibodies, Mon… Ofatumumab Rituximab
Lymphoma Lymphoma, B-Cel… Lymphoma, Non-H… Non-Hodgkin's L…
The study stopped due to futility.
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NCT01025648
Details
2018-05-16
Interventional
1/29 
Epinephrine Epinephryl bora… Racepinephrine
Asthma
Optimization of protocol
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NCT02013791
Details
2018-05-15
Interventional
255 
Cyclosporine Cyclosporins
Dry Eye Syndrom… Eye Diseases Keratoconjuncti…
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NCT02820493
Details
2018-05-14
Interventional
40 
Vedolizumab
Crohn Disease
Internal problems
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NCT02635074
Details
2018-05-14
Interventional
12 
Cytarabine Ibrutinib Idarubicin
Leukemia Leukemia, Myelo… Leukemia, Myelo… Recurrent Adult…
safety
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NCT02372240
Details
2018-05-11
Interventional
1/215 
Dexamethasone
Multiple Myelom… Neoplasms, Plas…
Dose limiting tox is observed. Study put on full clinical hold.
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NCT01804777
Details
2018-05-11
Interventional
19 
Amiloride Hydrochlorothia…
Diabetes Mellit… Diabetes Mellit… Hypertension Proteinuria Type II Diabete…
Currently closed for data analysis.
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