Friedrichs, M. (2023). A web-based annotation tool for clinical trial failure reasons. GMS Medizinische Informatik, Biometrie Und Epidemiologie, 19, Doc02. doi: 10.3205/mibe000241

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7805 Trials matched filter criteria

Status:   Withdrawn   Suspended   Terminated
Trial Updated /
Type
Status Phase Were
Results
Reported
Reported
Actual
Enrollment
(MeSH) Terms Why Stopped
Limitations And Caveats
Annotator decisions
NCT01925612
Details
2018-06-21
Interventional
287 
Antibodies, Mon… Brentuximab Ved… Cyclophosphamid… Doxorubicin Prednisone Rituximab Vincristine
Lymphoma Lymphoma, B-Cel… Lymphoma, Large… Lymphoma, B-cel… Lymphoma, Large…
Sponsor decision based on portfolio prioritization and changing treatment landscape in frontline DLBCL
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NCT02015637
Details
2018-06-20
Interventional
3460 
Ceftriaxone Delafloxacin
Gonorrhea
-
-
NCT01929317
Details
2018-06-20
Interventional
381 
Ropinirole
Parkinson Disea…
-
-
NCT03149159
Details
2018-06-18
Interventional
20 
Ipilimumab Nivolumab
Carcinoma Carcinoma, Rena… Clear Cell Rena… Metastatic Rena…
This study is withdrawn due to feasibility issues.
-
NCT02712775
Details
2018-06-18
Interventional
40 
Minocycline
Liver Diseases Liver Disease
Study logistics
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NCT00262132
Details
2018-06-18
Interventional
3-
Mycophenolic Ac…
Sarcoidosis Sarcoidosis, Pu… Pulmonary Sarco…
-
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NCT02702960
Details
2018-06-15
Interventional
20 
Antilymphocyte … Cyclophosphamid… Fludarabine Mesna Mycophenolic Ac… Prednisone Tacrolimus
Carcinoma Carcinoma, Hepa… Fibrolamellar H… Hepatocellular … Hepatocellular …
This study was withdrawn due to lack of necessary resources from the liver transplant surgical group.
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NCT02532010
Details
2018-06-15
Interventional
213 
Cytarabine Decitabine
Leukemia Leukemia, Myelo… Leukemia, Myelo… Acute Myeloid L…
The study was put on clinical hold by the sponsor since Feb 9th 2016, and was later decided not to re-open due to financial constraints.
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NCT02204722
Details
2018-06-15
Interventional
455 
Imatinib Mesyla…
Leukemia Leukemia, Myelo… Leukemia, Myelo… Chronic Myeloid…
Sponsor's decision to halt the study.
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NCT00403780
Details
2018-06-15
Interventional
418 
Pregabalin
Arterial Occlus… Chronic Limb-Th… Ischemia Arterial Occlus… Critical Limb I… Pain
low inclusion rate
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NCT03059277
Details
2018-06-14
Interventional
40 
Aflibercept
Edema Macular Edema Diabetic Macula…
Site investigator decided to not move forward with study.
-
NCT02203630
Details
2018-06-13
Interventional
417 
Norepinephrine Oxymetazoline Phenylephrine
Arrhythmias, Ca… Shock Shock, Septic Tachycardia Arrhythmia Sepsis Septic Shock
Slow enrollment; Lack of support and equipoise
Study was terminated early due to slow enrollment, lack of support and equipoise. PI left Vanderbilt and the record was completed with data recorded in REDCap.
NCT01183468
Details
2018-06-13
Interventional
117 
Alpha 1-Antitry… Protein C Inhib…
Diabetes Mellit… Diabetes Mellit…
Due to lack of mechanistic signal and competing industry studies
This (Part 1) was the drug dosing portion of the study; however, due to lack of a mechanistic signal and competing industry studies, the study was terminated and the trial portion (Part II, NCT01183455) was withdrawn.
NCT00059228
Details
2018-06-13
Interventional
212 
Estradiol Estradiol 17 be… Estradiol 3-ben… Polyestradiol p…
Depression Depression, Pos… Depressive Diso… Postpartum Depr…
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NCT03110900
Details
2018-06-11
Interventional
42 
Haloperidol Haloperidol dec… Lorazepam Loxapine
Psychomotor Agi… Agitation,Psych… Haloperidol Cau… Lorazepam Causi… Loxapine Causin…
Sponsor Withdrawal
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NCT01661322
2007-006749-42
Details
2018-06-11
Interventional
33096 
Aspirin Clopidogrel
Ischemic Stroke Stroke
Trial reached a definitive answer ahead of full recruitment.
-
NCT03105349
Details
2018-06-08
Interventional
40 
Elbasvir-grazop… Grazoprevir Ribavirin Sofosbuvir
Hepatitis C Hepatitis C, Ch… HCV
No availability of investigational medication.
-
NCT00955305
Details
2018-06-06
Interventional
2
[1 Refs]
175 
Bevacizumab Carboplatin Paclitaxel
Adenocarcinoma … Adenocarcinoma,… Carcinoma Carcinoma, Non-… Lung Neoplasms Bronchioloalveo… Large Cell Lung… Lung Adenocarci… Recurrent Non-S… Stage IV Non-Sm…
The study was closed to accrual due to the end of the clinical development program with cixutumumab.
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NCT03183596
Details
2018-05-31
Interventional
30 
Bupivacaine Dexamethasone
Pain, Postopera…
Principal investigator determination
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NCT02705872
Details
2018-05-31
Interventional
20 
Dsuvia Levobupivacaine Sufentanil
First Child Del…
Change in guidelines
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