Friedrichs, M. (2023). A web-based annotation tool for clinical trial failure reasons. GMS Medizinische Informatik, Biometrie Und Epidemiologie, 19, Doc02. doi: 10.3205/mibe000241

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Trial ID Phase Status Type
Results Reported Result Refs Exist Enrollment From To
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7805 Trials matched filter criteria

Status:   Withdrawn   Suspended   Terminated
Trial Updated /
Type
Status Phase Were
Results
Reported
Reported
Actual
Enrollment
(MeSH) Terms Why Stopped
Limitations And Caveats
Annotator decisions
NCT00052715
Details
2018-07-18
Interventional
2
[1 Refs]
31 
Poly ICLC
Central Nervous… Glioblastoma Nervous System … Brain and Centr…
prematurely discontinued after results of the EORTC phase-3 study defined the SOC for newly diagnosed GMB pts as RT plus concomitant and adjuvant TMZ
Enrollment was prematurely discontinued after the results of the EORTC phase-3 study defined the standard of care for newly diagnosed glioblastoma patients as radiotherapy plus concomitant and adjuvant temozolomide (2005)
NCT03343977
Details
2018-07-17
Interventional
1/20 
Docetaxel
Hypersensitivit… Prostatic Neopl… Metastatic Horm…
Study withdrawn for technical reasons
-
NCT02629094
Details
2018-07-17
Interventional
2
[1 Refs]
5 
Eplerenone
Fatty Liver HIV Infections Cardiac Steatos… Hepatic Steatos…
-
-
NCT01006252
Details
2018-07-17
Interventional
3336 
Paclitaxel
Melanoma
More possibly treatment-related deaths on tasisulam-sodium arm.
-
NCT02796547
Details
2018-07-13
Interventional
20 
Levobupivacaine
Episiotomy
Lack of human ressources
-
NCT02345460
Details
2018-07-13
Interventional
21 
Calcium Fluorouracil Irinotecan Leucovorin Levoleucovorin Oxaliplatin
Adenocarcinoma Neoplasms Pancreatic Neop… Pancreatic Aden… Poorly Differen… Resectable Panc… Stage IA Pancre… Stage IB Pancre… Stage IIA Pancr… Stage IIB Pancr… Stage III Pancr… Undifferentiate…
Competing studies
-
NCT01921751
Details
2018-07-13
Interventional
220 
Albumin-Bound P… Capecitabine Gemcitabine Paclitaxel
Pancreatic Neop… Pancreatic Aden… Stage III Pancr…
Trial would not be completed in a reasonable timeframe per CTEP guidelines
This study terminated early with only 20 registered (346 planned) and 13 randomized (288 planned). Follow-up forms were collected on only 3 patients.
NCT02069080
Details
2018-07-12
Interventional
12 
Plerixafor
Cancer
-
-
NCT00386399
Details
2018-07-12
Interventional
20 
Mitomycin Mitomycins
Pancreatic Neop… Pancreatic Canc…
All consented subjects tested negative for the BRCA2 mutation, therefore, did not meet criteria to start the study, resulting in withdrawal by PI
-
NCT00268450
Details
2018-07-12
Interventional
221 
Bevacizumab Gemcitabine Paclitaxel
Urinary Bladder… Bladder Cancer
-
-
NCT01975376
2013-002646-36
Details
2018-07-11
Interventional
316784 
Bococizumab
Cardiovascular … Cardiovascular …
See Detailed Description
As specified in statistical analysis plan, due to discontinuation of the bococizumab clinical development program, health care resource utilization endpoints were not evaluated.
NCT02767752
Details
2018-07-10
Interventional
221 
Capecitabine Gemcitabine
Pancreatic Neop… Pancreatic Canc…
Poor accrual and change of SOC (FOLFIRINOX in adjuvant setting)
-
NCT02724150
Details
2018-07-10
Interventional
40 
Omeprazole
Hemorrhage Peptic Ulcer Peptic Ulcer He… Ulcer Gastroduodenal … Marginal Ulcer
No participants enrolled
-
NCT02479204
Details
2018-07-10
Interventional
110 
Atenolol Diltiazem
Healthy Subject…
Based on results from the pilot phase, the study is terminated. No safety events leading to discontinuation were reported
-
NCT00646659
2006-004189-14
Details
2018-07-09
Interventional
247 
Carboplatin Cetuximab Docetaxel Fluorouracil
Head and Neck N… Head and Neck C…
Recruitment was suspended prematurely for safety concerns and closed after IDMC review
-
NCT00458276
Details
2018-07-09
Interventional
3274 
Tezosentan
Heart Diseases Hypertension Hypertension, P…
6 month vital status report not collected after 28 day follow up analysis indicated no difference between placebo & tezosentan
-
NCT00302731
Details
2018-07-06
Interventional
221 
Estradiol Estradiol 17 be… Estradiol 3-ben… Estrogens Hormones Polyestradiol p… Progesterone
Menopause
-
-
NCT02014545
Details
2018-07-05
Interventional
20 
Lucanthone
Brain Neoplasms Carcinoma, Non-… Lung Neoplasms Neoplasm Metast… Brain Metastase… Non-small Cell …
Pending resolution of study drug issues
-
NCT01910428
Details
2018-07-05
Interventional
114 
Asparaginase Eryaspase
Leukemia Leukemia, Lymph… Lymphoma Precursor Cell … Acute Lymphobla… Lymphoblastic L…
Sponsor decision based off site/PI feedback about
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NCT01814059
Details
2018-07-05
Interventional
14 
Sirolimus
Digestive Syste… Eosinophilic Es… Esophagitis Gastroenteritis Gastrointestina… Eosinophilic Ga…
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