Friedrichs, M. (2023). A web-based annotation tool for clinical trial failure reasons. GMS Medizinische Informatik, Biometrie Und Epidemiologie, 19, Doc02. doi: 10.3205/mibe000241

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Trial ID Phase Status Type
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7805 Trials matched filter criteria

Status:   Withdrawn   Suspended   Terminated
Trial Updated /
Type
Status Phase Were
Results
Reported
Reported
Actual
Enrollment
(MeSH) Terms Why Stopped
Limitations And Caveats
Annotator decisions
NCT03163784
Details
2018-11-15
Interventional
1/20 
Anti-Bacterial … Antibiotics, An…
Dysbiosis Inflammation HIV/AIDS
The study closed because of shifting research priorities and interests.
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NCT00310388
2006-000956-42
Details
2018-11-15
Interventional
3376 
Ezogabine
Epilepsy
No longer any benefit in collecting data since retigabine has been withdrawn from market.
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NCT03161041
Details
2018-11-14
Interventional
20 
Bevacizumab Oxaliplatin
Carcinoma Colorectal Carc…
CHU Lyon will join as a participating center (and as national French coordinator) as a part of the BEV-IP study ongoing study EudraCT-number 2014-004257-14.
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NCT02596334
Details
2018-11-13
Interventional
3158 
Abacavir Dolutegravir Lamivudine
HIV
5 patients on tivicay had virological failure
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NCT02268825
Details
2018-11-13
Interventional
139 
Pembrolizumab
Gastrointestina… Advanced GI Can…
Merck requested to change MK-3475 dosing schedule; PI decided to close instead
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NCT01630564
Details
2018-11-13
Interventional
12 
Aldesleukin Interleukin-2
Hematologic Neo… Hematopoietic a…
-
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NCT00102622
NCT02157870
Details
2018-11-13
Interventional
118 
Paclitaxel
Carcinoma, Ovar… Ovarian Neoplas… Ovarian Cancer
Phase I/II study that did not progress to Phase II
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NCT01740947
2011-002211-28
Details
2018-11-09
Interventional
4485 
Amphotericin B Colistin Liposomal ampho… Tobramycin
Colorectal Neop… Colorectal Canc…
Superiority was no longer attainable
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NCT00791271
NCT02605473
Details
2018-11-09
Interventional
117 
Decitabine Interferon alph… Interferon-alph… Interferons Peginterferon a…
Melanoma
-
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NCT00734526
Details
2018-11-09
Interventional
118 
Sorafenib Temozolomide
Glioblastoma Gliosarcoma
-
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NCT00895960
NCT02661113
Details
2018-11-08
Interventional
116 
Dasatinib Temozolomide
Brain Diseases Central Nervous… Glioblastoma CNS Disease
Sponsor withdrew support; Study did not progress to Phase II.
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NCT01855724
2012-001705-24
Details
2018-11-07
Interventional
229 
Gemcitabine
Carcinoma Cholangiocarcin… Gallbladder Neo… Biliary Carcino… Gallbladder Car…
-
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NCT01155479
2009-013552-72
Details
2018-11-07
Interventional
3
[1 Refs]
1022 
Rasagiline
Parkinson Disea…
Termininated for business reasons
-
NCT00693472
Details
2018-11-07
Interventional
246 
Cholinergic Ant… Haloperidol Haloperidol dec… Propranolol
Akathisia, Drug… Movement Disord… Psychomotor Agi… Antipsychotic A…
-
The study was terminated early by the sponsor due to lack of enrollment.
NCT00083772
Details
2018-11-07
Interventional
49 
Natriuretic Pep…
Cardiovascular … Heart Diseases Heart Failure Heart Failure, … Acute Heart Fai… Cardiovascular … Congestive Hear… Diastolic Heart… Heart Disease
-
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NCT01215227
2009-015162-57
Details
2018-11-06
Interventional
3839 
Rasagiline
Parkinson Disea… Idiopathic Park…
-
This study was terminated early due to the lack of efficacy of preladenant in the parent studies NCT1155466 and NCT01227265.
NCT02652156
Details
2018-11-02
Interventional
314 
Bupivacaine Ropivacaine
Pain, Postopera…
Operational barriers at the site.
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NCT00758368
Details
2018-11-02
Interventional
20 
Apomorphine
Parkinson Disea… Parkinson's Dis…
Inadequate support to conduct the study
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NCT00197145
Details
2018-11-02
Interventional
324 
Aplaviroc
Acquired Immuno… HIV Infections Infection, Huma…
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Study was early terminated prior to the completion of enrollment due to treatment-emergent hepatotoxicity that occurred among some participants receiving APL.
NCT00037882
Details
2018-11-01
Interventional
21 
Interferon alph… Interferon-alph… Interferons Peginterferon a…
Leukemia Leukemia, Myelo… Leukemia, Myelo… Leukemia, Myelo…
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