Friedrichs, M. (2023). A web-based annotation tool for clinical trial failure reasons. GMS Medizinische Informatik, Biometrie Und Epidemiologie, 19, Doc02. doi: 10.3205/mibe000241

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7805 Trials matched filter criteria

Status:   Withdrawn   Suspended   Terminated
Trial Updated /
Type
Status Phase Were
Results
Reported
Reported
Actual
Enrollment
(MeSH) Terms Why Stopped
Limitations And Caveats
Annotator decisions
NCT03591744
Details
2018-12-19
Interventional
10 
BB 1101 Bortezomib Daratumumab Dexamethasone Dexamethasone a… Doxorubicin Ichthammol Lenalidomide Liposomal doxor…
Leukemia Leukemia, Plasm… Plasma Cell Leu…
Budgetary constraints
-
NCT02556463
Details
2018-12-19
Interventional
153 
Durvalumab MEDI9197
Neoplasms CTCL Cancer Solid Tumors
Company strategy
-
NCT02365493
Details
2018-12-19
Interventional
3358 
Cefazolin Cloxacillin Floxacillin Lactams beta-Lactams
Staphylococcal … Methicillin-Res…
Recommendation of the Data Safety Monitoring Committee
-
NCT02311777
Details
2018-12-19
Interventional
30 
Ketamine Pregabalin
Phantom Limb Phantom Pain
Preoperative period is very short time
-
NCT01552798
Details
2018-12-19
Interventional
39 
Acetaminophen Aspirin
Headache Tension-Type He…
-
-
NCT01523639
2011-001010-34
Details
2018-12-19
Interventional
28 
Metformin
Colorectal Neop… Fatty Liver Colorectal Canc… Steatohepatitis
Prematurely due to slow recruitment (07/08/2013). Newly defined study end=LPLV=05/11/2013. ABCSG guaranteed completed treatment period for ethical reasons.
-
NCT01514838
Details
2018-12-17
Interventional
346 
Acarbose Ipragliflozin
Diabetes Mellit… Diabetes Mellit… Type II Diabete…
Discontinued due to company's strategic reason
-
NCT03398018
Details
2018-12-14
Interventional
40 
Adrenocorticotr…
Dry Eye Syndrom… Keratoconjuncti… Keratoconjuncti…
Change of direction
-
NCT02374099
Details
2018-12-14
Interventional
297 
Azacitidine Cc-486 Fulvestrant
Breast Neoplasm…
-
-
NCT02236481
Details
2018-12-14
Interventional
441 
Interleukin 1 R…
Arthritis Arthritis, Rheu… Diabetes Mellit… Diabetes Mellit…
Decision of the Sponsor for Early Benefits
-
NCT00128895
Details
2018-12-13
Interventional
4
[1 Refs]
131 
Azathioprine
Vasculitis
-
-
NCT02785900
2015-003482-28
Details
2018-12-12
Interventional
3240 
Azacitidine Decitabine
Leukemia Leukemia, Myelo… Leukemia, Myelo… Acute Myeloid L…
Due to safety; specifically a higher rate of deaths, including fatal infections, in the SGN33A arm versus the control arm
-
NCT02722083
Details
2018-12-12
Interventional
21 
Chlorpheniramin…
Rhinitis Rhinitis, Aller…
-
-
NCT03349346
2017-001468-39
Details
2018-12-11
Interventional
10 
Carboplatin Etoposide Idelalisib Ifosfamide Rituximab
Lymphoma Lymphoma, B-Cel… Lymphoma, Large… Diffuse Large B… Mediastinal B-c…
The European Medical Agency granted a Paediatric Investigational Product-specific waiver on the grounds that idelalisib is likely to be unsafe in paediatrics
-
NCT00924807
Details
2018-12-11
Interventional
1/24 
Bicalutamide Leuprolide Sorafenib
Prostatic Neopl… Prostate Cancer
Sponsor closed the trial
Data of zero ("0") participants were analyzed due to lack of funding and prematurely terminating the study by sponsor. All subjects are following up in the clinic off the study. Early termination leading to small number of subjects analyzed.
NCT01374217
Details
2018-12-10
Interventional
214 
Clarithromycin Dexamethasone Lenalidomide Tadalafil
Multiple Myelom… Neoplasms, Plas…
early stopping rule
-
NCT03531281
Details
2018-12-07
Interventional
10 
Cyclophosphamid… Etoposide Etoposide phosp… Mitogens Podophyllotoxin Sirolimus Tacrolimus
Hematologic Neo… Hematopoietic C… Hematopoietic a…
Administratively withdrawn
-
NCT02401594
2015-000981-70
Details
2018-12-07
Interventional
33608 
Enoxaparin Rivaroxaban
Non-major Ortho…
Remaining outdated treatments and additional costs too high for new manufacturing
-
NCT01281956
Details
2018-12-07
Interventional
212 
Naluzotan
Epilepsies, Par… Epilepsy Epilepsy, Tempo… Partial Epileps…
-
-
NCT00100828
Details
2018-12-06
Interventional
26 
Irinotecan
Thyroid Neoplas… Head and Neck C…
Closed due to early stopping rule
-