Friedrichs, M. (2023). A web-based annotation tool for clinical trial failure reasons. GMS Medizinische Informatik, Biometrie Und Epidemiologie, 19, Doc02. doi: 10.3205/mibe000241

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7805 Trials matched filter criteria

Status:   Withdrawn   Suspended   Terminated
Trial Updated /
Type
Status Phase Were
Results
Reported
Reported
Actual
Enrollment
(MeSH) Terms Why Stopped
Limitations And Caveats
Annotator decisions
NCT02422940
Details
2019-01-22
Interventional
3294 
4-Aminopyridine
Ischemic Stroke Post-ischemic S…
-
-
NCT02205398
2014-000579-20
Details
2019-01-22
Interventional
113 
Cetuximab
Carcinoma, Squa… Colorectal Neop… Squamous Cell C… Metastatic Colo… Squamous Cell C…
-
-
NCT03808168
Details
2019-01-18
Interventional
20 
Nivolumab
Uterine Cervica… Cervix Uteri--D…
FDA has withdrawn the IND application- requesting protocol changes
-
NCT02148367
Details
2019-01-18
Interventional
20 
Epoetin Alfa
Brain Injuries Brain Injuries,… Traumatic Brain…
Publication of recent trials showing no effect of EPO in TBI.
-
NCT00499733
Details
2019-01-18
Interventional
119 
Cyclophosphamid…
Cancer
The study was terminated per PI decision.
-
NCT01198379
Details
2019-01-17
Interventional
40 
Aspirin
Kidney Failure,… End-Stage Renal…
No participants enrolled
-
NCT01912378
Details
2019-01-16
Interventional
10 
Oxytocin
Autistic Disord… Autism Disorder
unable to launch the study due to lack of participation with Autism Clinic
-
NCT03803163
Details
2019-01-14
Interventional
120 
Treprostinil
Healthy Volunte…
Discontinued early due to local tolerance expectations not being met.
-
NCT02975921
Details
2019-01-11
Interventional
40 
Povidone Povidone-Iodine
Heart Failure Pleural Effusio… Pleural Effusio… Malignant Pleur… Pleural Effusio… Pleural Effusio… Pleural Effusio… Pleurodesis
The site decided not to proceed with the protocol.
-
NCT02407314
Details
2019-01-11
Interventional
426 
Aspirin Ticagrelor
Peripheral Arte… Peripheral Vasc…
AZ discontinued study
-
NCT02220088
Details
2019-01-11
Interventional
2/3
[7 Refs]
79 
Fluorouracil Leucovorin Oxaliplatin Sorafenib
Carcinoma, Hepa… Hepatocellular …
protocol violation
-
NCT03324243
Details
2019-01-10
Interventional
20 
Crenolanib Cytarabine Fludarabine
Leukemia, Myelo… Relapsed/Refrac…
Withdrawn: Study halted prior to enrollment of first participant
-
NCT02657447
2013-003908-39
Details
2019-01-10
Interventional
10 
1,4,7,10-tetraa…
Lymphoma Lymphoma, Non-H… Non-Hodgkin Lym…
Study is no longer relevant
-
NCT02109445
2013-005574-21
Details
2019-01-10
Interventional
23 
Albumin-Bound P… Gemcitabine Nirogacestat Paclitaxel
Adenocarcinoma Metastatic Canc…
The study was terminated on 24JUN15 due to change in strategy of PF-03084014 development.No safety/efficacy concerns were behind the reason of trial termination
Due to early termination of the study, only 3 participants were enrolled. Phase 2 was not carried out. As such, there is limited data for Phase 1 and no data for Phase 2.
NCT01413854
2010-021024-10
Details
2019-01-10
Interventional
1/20 
Diclofenac
Depression Depression Suic…
Not enough recources.
-
NCT01284335
Details
2019-01-10
Interventional
1234 
Docetaxel Erlotinib Hydro… Gemcitabine Temozolomide
Neoplasms Advanced Solid …
Study was terminated due to the termination of tasisulam development.
This study was terminated early due to termination of development of the tasisulam compound. All participants were considered to have completed the study upon the completion of one cycle of treatment.
NCT00547443
NCT00975260
Details
2019-01-10
Interventional
1/20 
Carboplatin Paclitaxel Sorafenib
Carcinoma, Non-… Lung Neoplasms Lung Cancer
Withdrawn as the sponsor has stopped the drug for NSCLC population
-
NCT03173365
Details
2019-01-09
Interventional
22 
Brimonidine Tar…
Hand-Foot Syndr… Syndrome Hand-foot Syndr…
It is no longer practicable to complete the trial
-
NCT02901106
Details
2019-01-09
Interventional
411 
Dimethyl Fumara…
Multiple Sclero… Multiple Sclero… Sclerosis
Another surveillance protocol was initiated by the OFSEP (OFSEP cohort) which allows to follow all the patients, whatever their treatment.
-
NCT02730195
Details
2019-01-09
Interventional
29 
Pioglitazone Tyrosine Kinase…
Leukemia Leukemia, Myelo… Leukemia, Myelo… Chronic Myeloge… Recurrent Chron…
-
Study was terminated early due to previous principal investigator leaving institution.