Friedrichs, M. (2023). A web-based annotation tool for clinical trial failure reasons. GMS Medizinische Informatik, Biometrie Und Epidemiologie, 19, Doc02. doi: 10.3205/mibe000241

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7805 Trials matched filter criteria

Status:   Withdrawn   Suspended   Terminated
Trial Updated /
Type
Status Phase Were
Results
Reported
Reported
Actual
Enrollment
(MeSH) Terms Why Stopped
Limitations And Caveats
Annotator decisions
NCT01876251
2013-000659-41
Details
2019-03-15
Interventional
130 
Docetaxel Nirogacestat
Breast Neoplasm… Breast Cancer M…
The study was terminated on June 24th, 2015 due to change in strategy of PF-03084014 development. There were no safety/efficacy concerns behind the decision.
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NCT01760252
Details
2019-03-15
Interventional
217 
Capecitabine Irinotecan Oxaliplatin
Adenocarcinoma Metastatic Panc…
-
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NCT01370694
2011-000386-13
Details
2019-03-15
Interventional
17 
Cyclophosphamid… Prednisolone Vincristine
Lymphoma Lymphoma, Folli… Follicular Lymp…
The study was terminated for business reasons.
The study was terminated for business reasons. Not all planned analyses were performed
NCT03028909
Details
2019-03-14
Interventional
20 
MEDI8852 Oseltamivir
Influenza, Huma… Sprains and Str… Influenza - Typ…
Study is withdrawn due to company decision.
-
NCT01283386
Details
2019-03-14
Interventional
426 
Chlorambucil Cyclophosphamid… Fludarabine Rituximab
Leukemia Leukemia, Lymph… Leukemia, Lymph… Lymphocytic Leu…
-
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NCT00561067
Details
2019-03-14
Interventional
310 
Epoetin Alfa Methylprednisol… Methylprednisol… Methylprednisol… Prednisolone Prednisolone ac… Prednisolone he… Prednisolone ph…
Spinal Cord Inj… Spinal Cord Inj…
Italian Medicines Agency decision
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NCT03805672
Details
2019-03-13
Interventional
44 
Enoxaparin Enoxaparin sodi…
Thrombosis Venous Thrombos… Blood Clots Deep Vein Throm…
Terminated due to low enrollment because of decrease in DVT rates.
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NCT02630472
Details
2019-03-13
Interventional
1/210 
Quinine
Rhinitis Sinusitis
Institutional decision
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NCT02407223
2015-000289-67
Details
2019-03-13
Interventional
3356 
Ustekinumab
Axial Spondyloa… Non-Radiographi… Spondylarthriti… Spondylitis Spondylitis, An… Nonradiographic…
This study was stopped because ustekinumab did not achieve key endpoints in a related study. The safety profile was consistent with past ustekinumab studies.
The study was discontinued before it was fully enrolled, therefore, the interpretation of the efficacy data is limited.
NCT00662077
Details
2019-03-13
Interventional
40 
Ibandronic Acid
Osteoporosis HIV Infections
Financial difficulties
-
NCT03809897
Details
2019-03-12
Interventional
40 
Nicotine Varenicline
Mental Disorder… Problem Behavio… Psychiatric Dis… Tobacco Use Ces…
Budget not sufficient to cover the study scope proposed and recruitment rates expected to be no sufficient.
-
NCT03369782
Details
2019-03-12
Interventional
40 
Rocuronium
Pain, Postopera… Postoperative P… Surgery
refocusing of research priorities
-
NCT02948101
Details
2019-03-12
Interventional
20 
Antibodies Antibodies, Mon… Cyclophosphamid…
Carcinoma Recurrence Recurrent Fallo… Recurrent Ovari… Recurrent Prima…
PI's request
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NCT02525302
Details
2019-03-12
Interventional
210 
Halofuginone
Muscular Dystro… Muscular Dystro… Duchenne Muscul…
Dosing stopped
-
NCT01191034
Details
2019-03-12
Interventional
1/22 
Imiquimod
Melanoma Metastatic Mela…
Completion after 2 patients then stop due to end of validity of vaccine peptide
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NCT03468829
2017-003356-23
Details
2019-03-11
Interventional
20 
Gontivimab
Communicable Di… Infections Respiratory Tra… Respiratory Syn…
ALX-0171 development program was stopped
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NCT03705858
Details
2019-03-08
Interventional
10 
Lintuzumab
Leukemia Leukemia, Myelo… Leukemia, Myelo… Acute Myeloid L…
Due to difficulty in finalizing the contract
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NCT03196921
Details
2019-03-08
Interventional
1/20 
Amphotericin B Liposomal ampho…
Communicable Di… Infections Cryptococcal In…
Protocol redundancy
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NCT03187691
Details
2019-03-08
Interventional
20 
Amphotericin B Liposomal ampho…
Leukemia Leukemia, Lymph… Precursor Cell … Acute Lymphobla… Acute Myeloid L…
Protocol redundancy
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NCT03167957
Details
2019-03-08
Interventional
20 
Amphotericin B Liposomal ampho…
Candidiasis Candidiasis, Vu… Communicable Di… Infections Mycoses Vulvovaginitis Vulvovaginal Ca… Yeast Infection Yeast Infection…
No longer target indication
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