Friedrichs, M. (2023). A web-based annotation tool for clinical trial failure reasons. GMS Medizinische Informatik, Biometrie Und Epidemiologie, 19, Doc02. doi: 10.3205/mibe000241

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7805 Trials matched filter criteria

Status:   Withdrawn   Suspended   Terminated
Trial Updated /
Type
Status Phase Were
Results
Reported
Reported
Actual
Enrollment
(MeSH) Terms Why Stopped
Limitations And Caveats
Annotator decisions
NCT03268278
Details
2019-04-23
Interventional
110 
Anesthetics Anesthetics, Lo… Buprenorphine Epinephrine Lidocaine
Pain, Postopera… Postoperative P…
Loss of interest
-
NCT03246399
Details
2019-04-23
Interventional
16 
Lorecivivint
Intervertebral … Spinal Diseases Degenerative Di…
Study stopped due to business reasons, following full enrollment of the first dose cohort.
-
NCT02087085
2013-003320-36
Details
2019-04-23
Interventional
2310 
Brimonidine Tar…
Atrophy Geographic Atro… Macular Degener…
-
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NCT02595840
2014-001983-36
Details
2019-04-19
Interventional
24 
Afatinib Pemetrexed
Carcinoma, Non-… Non-small-cell …
Futility
-
NCT01756924
Details
2019-04-19
Interventional
214 
Anti-Bacterial … Cefazolin Ceftaroline Ceftriaxone Ciprofloxacin Daptomycin Fusidic Acid Levofloxacin Linezolid Nafcillin Oxacillin Rifampin Trimethoprim, S… Vancomycin
Arthritis, Infe… Communicable Di… Infections Infected Spacer… Prosthetic Join… Prosthetic Join…
This study has been terminated; alternative study designs are being considered. Fusidic acid remains available under an Expanded Access Protocol.
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NCT03490019
Details
2019-04-18
Interventional
20 
Metformin
Bardet-Biedl Sy… Laurence-Moon S… Syndrome Vision Disorder… Vision, Low Visual Impairme…
unrealizable wishes of national authorities
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NCT03386838
2017-003059-46
Details
2019-04-18
Interventional
30 
Carboplatin Cetuximab Fluorouracil Linrodostat Nivolumab
Carcinoma, Squa… Squamous Cell C… Head and Neck C…
Business objectives have changed.
-
NCT02995512
Details
2019-04-18
Interventional
40 
Colchicine
Infarction Myocardial Infa…
feasibility
-
NCT02809755
Details
2019-04-18
Interventional
40 
Lidocaine
Shoulder Pain Obesity
While 33 people signed consent, no one was enrolled in the study, because none of these patients developed shoulder pain in the recovery room.
-
NCT01942187
Details
2019-04-18
Interventional
40 
Aripiprazole Bupropion
Depression Depressive Diso… Depressive Diso… Dysthymic Disor… Depressive Diso… Major Depressiv…
No participants enrolled.
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NCT01743755
2011-004566-14
Details
2019-04-18
Interventional
4413 
Dexamethasone
Pneumonia Community-acqui…
-
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NCT00924950
Details
2019-04-18
Interventional
435 
Betamethasone Calcitriol
Psoriasis Plaque Psoriasi… Psoriasis Vulga…
-
-
NCT03153813
Details
2019-04-17
Interventional
322 
Capsaicin
Osteoarthritis Osteoarthritis,… Pain
-
-
NCT03076684
Details
2019-04-17
Interventional
10 
Allopurinol
Hyperuricemia
Preliminary data collected and diets developed. Funding has ended and data used to support a larger application to test the hypothesis.
-
NCT02568683
2015-002731-17
Details
2019-04-17
Interventional
1/210 
Vincristine
Lymphoma Lymphoma, B-Cel… Lymphoma, Non-H… Non-Hodgkin Lym…
-
Because the study was terminated after enrolling only 10 participants, the dose expansion stage and the planned efficacy analyses were not conducted.
NCT01479465
2011-003754-61
Details
2019-04-17
Interventional
2266 
Fluorouracil Irinotecan Leucovorin
Adenocarcinoma Colorectal Neop… Colorectal Canc…
-
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NCT00701233
Details
2019-04-17
Interventional
20 
Botulinum Toxin…
Carpal Tunnel S… Syndrome
Unable to generate MD's and patients for this study
-
NCT03419559
Details
2019-04-16
Interventional
20 
Durvalumab
Carcinoma, Non-… Lung Neoplasms Non Small Cell …
The treatment landscape for NSCLC has evolved in the past year. An additional NSCLC arm will be added to the IOV-COM-202 study using TIL + pembrolizumab.
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NCT02738008
2014-004201-33
Details
2019-04-16
Interventional
212 
Entecavir Histamine Antag… Histamine H1 An… Tenofovir
Hepatitis Hepatitis A Hepatitis B Hepatitis B, Ch…
Company decision to discontinue trial
The decision to discontinue development of ARC-EXl-containing programs was not due to any safety findings in clinical studies.
NCT02604212
2014-004751-31
Details
2019-04-16
Interventional
232 
Entecavir Histamine Antag… Histamine H1 An… Tenofovir
Hepatitis Hepatitis A Hepatitis B Hepatitis B, Ch…
Company decision to discontinue trial
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