Friedrichs, M. (2023). A web-based annotation tool for clinical trial failure reasons. GMS Medizinische Informatik, Biometrie Und Epidemiologie, 19, Doc02. doi: 10.3205/mibe000241

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7805 Trials matched filter criteria

Status:   Withdrawn   Suspended   Terminated
Trial Updated /
Type
Status Phase Were
Results
Reported
Reported
Actual
Enrollment
(MeSH) Terms Why Stopped
Limitations And Caveats
Annotator decisions
NCT02421354
Details
2019-05-15
Interventional
28 
Nivolumab
Hepatomegaly Polycythemia Polycythemia Ve… Primary Myelofi… Splenomegaly Thrombocythemia… Thrombocytosis Myelofibrosis T… Polycythemia Ve…
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NCT02987920
Details
2019-05-14
Interventional
423 
Acetaminophen Celecoxib Dextromethorpha… Gabapentin Hydromorphone Ketorolac Levomethorphan Oxycodone Pantoprazole
Pain, Postopera…
The surgeon changed pain control protocol for all patients. Continued enrollment impossible under approved protocol.
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NCT02929498
2016-002294-35
Details
2019-05-14
Interventional
1/27 
Azacitidine
Myelodysplastic… Preleukemia Syndrome Myelodysplastic…
The risk benefit in the study population does not favor continuation of the study
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NCT02410382
Details
2019-05-14
Interventional
279 
Dexamethasone
Carcinoma, Non-… Lung Neoplasms Head and Neck C… Non-small Cell …
IRB suspension, did not resume
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NCT02258529
Details
2019-05-14
Interventional
210 
Idelalisib Rituximab
Leukemia, Lymph… Lymphoma Lymphoma, Folli… Follicular Lymp… Small Lymphocyt…
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Due to the early termination of the study, efficacy data were not available for all participants, and therefore the prespecified analyses were not conducted.
NCT01756560
Details
2019-05-14
Interventional
42 
Bupivacaine
Duration of Pai…
Unable to continue research due to time constraints
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NCT01328002
Details
2019-05-14
Interventional
2116 
Levomilnacipran Milnacipran
Fibromyalgia Myofascial Pain… Primary Fibromy…
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Due to the early termination of the study, no firm conclusions about the use of milnacipran in pediatric patients for the treatment of primary fibromyalgia can be drawn.
NCT03457753
Details
2019-05-13
Interventional
20 
Riluzole
Amyotrophic Lat… Motor Neuron Di… Sclerosis ALS
The Sponsor stopped the study due to a change in study plans
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NCT03752190
Details
2019-05-10
Interventional
40 
Cosyntropin
Adrenal Insuffi…
Change in personnel leading to inability to conduct study.
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NCT03645876
Details
2019-05-10
Interventional
212 
Capecitabine Oxaliplatin
Colorectal Neop… Metastatic Colo…
The study was terminated early due to company decision
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NCT03490916
Details
2019-05-10
Interventional
418 
Acetazolamide
Altitude Sickne… Edema Hypertension, P… Pulmonary Edema High Altitude P…
PI was unable to continue to gather data during the trip during to medical illness
Due to Investigator illness, although participants were enrolled, no participants were randomized to receive interventions and did not receive study drug.
NCT01875653
2015-001984-38
Details
2019-05-10
Interventional
34 
Molgramostim Sargramostim
Melanoma Stage III Melan… Stage IV Melano…
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NCT00814593
Details
2019-05-10
Interventional
20 
Carmustine
Central Nervous… Glioblastoma Nervous System … Brain and Centr…
Hoag Hospital ceased support.
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NCT00704821
Details
2019-05-10
Interventional
176 
Docetaxel
Neoplasms Advanced Cancer
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NCT02186301
Details
2019-05-07
Interventional
2/3100 
Erlotinib Hydro…
Carcinoma, Non-… Non-Small Cell …
Sponsor discontinued development of CO-1686 for NSCLC
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NCT01536717
2011-004307-20
Details
2019-05-07
Interventional
436 
Carticaine
Aortic Valve Di… Heart Septal De… Heart Septal De… Aortic Valve Di… Atrial Septal D… Diseases of Mit… Intracardiac My…
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NCT03775707
Details
2019-05-06
Interventional
20 
Antibodies Lenvatinib
Carcinoma Carcinoma, Hepa… Hepatocellular …
Protocol modification
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NCT03752138
Details
2019-05-06
Interventional
10 
Decitabine
Leukemia Leukemia, Myelo… Leukemia, Myelo… Recurrent Acute… Refractory Acut…
The supporting pharamceutical company elected not to pursue this study at this time.
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NCT02895529
Details
2019-05-06
Interventional
461 
Caspofungin Itraconazole
Hematologic Neo…
Study is a commitment for license renew, we target on Apr19 submission, considering timeline, a cut off should be scheduled in Apr18.
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NCT01403389
Details
2019-05-06
Interventional
28 
Eculizumab
Delayed Graft F… Delayed Functio…
After interim analysis, the pilot study was terminated and modified to a larger multicenter study (NCT01919346) to better assess efficacy.
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