Friedrichs, M. (2023). A web-based annotation tool for clinical trial failure reasons. GMS Medizinische Informatik, Biometrie Und Epidemiologie, 19, Doc02. doi: 10.3205/mibe000241

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Trial ID Phase Status Type
Results Reported Result Refs Exist Enrollment From To
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7805 Trials matched filter criteria

Status:   Withdrawn   Suspended   Terminated
Trial Updated /
Type
Status Phase Were
Results
Reported
Reported
Actual
Enrollment
(MeSH) Terms Why Stopped
Limitations And Caveats
Annotator decisions
NCT00327379
2005-003999-38
Details
2019-06-04
Interventional
354 
Aprotinin
Blood Loss, Sur… Hemorrhage Postoperative H…
-
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NCT03797443
Details
2019-05-31
Interventional
1/20 
Ascorbic Acid Gemcitabine Paclitaxel
Pancreatic Neop… Metastatic Panc…
Regulatory Review needed
-
NCT03908333
Details
2019-05-30
Interventional
1/20 
Albumin-Bound P… Ascorbic Acid Gemcitabine Paclitaxel
Adenocarcinoma Pancreatic Neop… Metastatic Panc… Pancreas Cancer Pancreatic Aden… Pancreatic Canc… Pancreatic Duct… Pancreatic Meta…
Request to close per funding sponsor. Site not moving forward with trial.
-
NCT03829696
Details
2019-05-30
Interventional
40 
Mifepristone Misoprostol Ulipristal acet…
Early Abortion
The study is not proceeding at this time.
-
NCT03432676
Details
2019-05-30
Interventional
20 
Pembrolizumab
Pancreatic Neop… ATM Gene Mutati… Deleterious BRC… Deleterious BRC… Homologous Reco… Pancreatic Duct… Stage II Pancre… Stage IIA Pancr… Stage IIB Pancr… Stage III Pancr… Stage IV Pancre…
Incyte (supporter of the study) is no longer going to support the study.
-
NCT02300935
Details
2019-05-30
Interventional
10 
Paclitaxel Trametinib
Melanoma
Study concept was terminated.
-
NCT01705483
Details
2019-05-30
Interventional
121 
Docetaxel Paclitaxel
Neoplasms Non-hematologic… Pharmacokinetic…
Based on the results of the Phase 1 data, the company decided not to pursue the development of this drug at this time.
-
NCT01588314
Details
2019-05-29
Interventional
20 
Gabapentin
Fabry Disease Neuralgia Neuropathic Pai…
No patients were enrolled. No data & no study results to report.
-
NCT02712944
Details
2019-05-28
Interventional
121 
Testosterone
Hypogonadism
Study stopped for procedural difficulties and lack of personnel
-
NCT03395132
Details
2019-05-22
Interventional
368 
Betamethasone Fusidic Acid
Dermatitis Dermatitis, Ato… Eczema Infected Atopic…
Due to business strategic reasons, LEO Pharma has decided to close down the FCF-38 trial.
-
NCT02684786
Details
2019-05-22
Interventional
10 
Lidocaine Reserpine
Hypertension Hypertension, P… Pulmonary Arter… Pulmonary Arter…
IRB did not approve
-
NCT01371344
2009-012259-21
Details
2019-05-22
Interventional
447 
Tacrolimus
Heart Transplan… Kidney Transpla… Liver Transplan…
Trial will not complete until at least 2025 and evolution of immunosuppressant therapy has made it unlikely that patients will convert from Modigraf to Prograf.
-
NCT01601184
2011-003372-37
Details
2019-05-21
Interventional
1/224 
Temozolomide
Medulloblastoma Activation of t… Histologically …
The number of successes is not reached at the end of first stage of the phase II. The study is stopped.
-
NCT01152021
Details
2019-05-21
Interventional
315 
Dexmedetomidine Propofol
Safety and Effi…
Publication of a similar study. Not ethical to continue.
The study was terminated (halted prematurely) due to publication of a similar study and it was deemed unethical to continue.
NCT00547300
Details
2019-05-21
Interventional
349 
Metoprolol Nebivolol
Hypertension
-
Study was terminated early due to administrative reasons. Formal analyses of primary and secondary endpoints were not conducted in this study.
NCT02991768
Details
2019-05-20
Interventional
29 
Budesonide
Diarrhea
Enrollment not continued
-
NCT02479880
2014-004939-39
Details
2019-05-20
Interventional
430 
Tenofovir
Hepatitis Hepatitis A Hepatitis B Hepatitis B, Ch…
-
-
NCT03408015
Details
2019-05-17
Interventional
40 
Lifitegrast
Dry Eye Syndrom… Eye Diseases Inflammation Keratoconjuncti… Keratoconjuncti… Contact Lens Co… Dry Eye Ocular Discomfo… Ocular Inflamma…
Study timing was poor.
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NCT01248299
2010-021439-16
Details
2019-05-16
Interventional
2105 
Cisplatin Docetaxel Fluorouracil Oxaliplatin
Esophageal Neop… Esophageal Squa… Squamous Cell C…
-
-
NCT02885441
Details
2019-05-15
Interventional
456 
Ketorolac
Pancreatitis Acute Pancreati…
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