Friedrichs, M. (2023). A web-based annotation tool for clinical trial failure reasons. GMS Medizinische Informatik, Biometrie Und Epidemiologie, 19, Doc02. doi: 10.3205/mibe000241

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7805 Trials matched filter criteria

Status:   Withdrawn   Suspended   Terminated
Trial Updated /
Type
Status Phase Were
Results
Reported
Reported
Actual
Enrollment
(MeSH) Terms Why Stopped
Limitations And Caveats
Annotator decisions
NCT02289144
Details
2019-07-30
Interventional
20 
Ceritinib
Thyroid Carcino… Thyroid Disease… Thyroid Neoplas… Locally Advance… Metastatic Anap…
study was on hold for protocol redesign; decided to not move forward with study.
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NCT00167180
NCT00303693
Details
2019-07-30
Interventional
257 
Cyclophosphamid…
Leukemia Leukemia, Lymph… Leukemia, Lymph… Leukemia, Myelo… Leukemia, Myelo… Multiple Myelom… Myelodysplastic… Precursor Cell … AML Leukemia, Lymph… Leukemia, Lymph… Leukemia, Myelo… Lymphomas Myelodysplastic…
Accrual Goal Met
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NCT02908516
Details
2019-07-29
Interventional
46 
Tranexamic Acid
Fractures, Bone Hemorrhage Hip Fractures Blood Loss
Study was terminated due to inability to recruit and collect follow up outcome data.
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NCT02912026
Details
2019-07-26
Interventional
10 
Olorofim
Aspergillosis Invasive Asperg…
Major change to study design
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NCT02613403
2015-001483-19
Details
2019-07-26
Interventional
2
[1 Refs]
94 
Ribavirin Uprifosbuvir
Communicable Di… Digestive Syste… Flaviviridae In… Gastrointestina… Hepatitis Hepatitis A Hepatitis C Hepatitis, Vira… Infections Liver Diseases RNA Virus Infec… Virus Diseases
-
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NCT01912261
Details
2019-07-26
Interventional
3121 
Iron
Fatigue
The study was stopped due to time constraints and resources
-
NCT00642694
Details
2019-07-26
Interventional
329 
Citalopram Dexetimide Escitalopram
Depression Depressive Diso… Depressive Diso… Sleep Initiatio… Insomnia Major Depressiv…
Enrollment discontinued based on mutually agreed upon decision by PI and funding sponsor
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NCT03361709
Details
2019-07-24
Interventional
40 
Dexamethasone
Corneal Endothe… Corneal Endothe… Dexamethasone A… Diabetes Mellit…
Inability to perform the study at present time.
-
NCT03074825
Details
2019-07-24
Interventional
15 
Chiauranib
Lymphoma Lymphoma, Non-H… Non-Hodgkin's L…
The results fell short of expectations.
-
NCT03010761
Details
2019-07-24
Interventional
290 
Escitalopram Moclobemide
Behavior, Addic… Addiction
all participants finished the trial
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NCT02853253
Details
2019-07-24
Interventional
40 
SMOFlipid
Bronchopulmonar… Premature Birth Preterm Neonate…
scientific question reconsidered
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NCT01646125
2012-001050-25
Details
2019-07-24
Interventional
259 
Docetaxel Pemetrexed
Carcinoma, Non-… Lung Neoplasms Advanced Non Sm…
An interim analysis was conducted in May-2014. Upon review of the data, the committee recommended study termination due to futility.
The data monitoring committee (DMC's) recommendation based on the Interim Analysis (IA) results to terminate the study early due to futility, data was not collected for this assessment on many of the secondary endpoints.
NCT00882076
Details
2019-07-24
Interventional
122 
Clofarabine Etoposide Etoposide phosp… Mitoxantrone
Leukemia
study closed prematurely
-
NCT02664961
Details
2019-07-23
Interventional
23 
Bevacizumab
Choriocarcinoma Gestational Tro… Neoplasms Trophoblastic N… Trophoblastic T… Epithelioid Tro… Gestational Tro… Placental Site …
Rare tumor type, patients eligible via expanded access.
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NCT02610062
Details
2019-07-23
Interventional
123 
AGS67E
Leukemia Leukemia, Myelo… Leukemia, Myelo… Acute Myeloid L…
Business decision by sponsor
-
NCT02543086
Details
2019-07-23
Interventional
18 
Piperaquine
Malaria Malaria, Falcip… Plasmodium Falc…
-
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NCT02111447
Details
2019-07-23
Interventional
46 
Isoflurane Propofol Sevoflurane
Delirium Emergence Delir… Delirium on Eme…
Not enough participants
none study not completed due to facility issues
NCT00668317
2006-004102-13
Details
2019-07-23
Interventional
35 
Omeprazole Ranitidine Ranitidine bism…
Bronchial Hyper… Cough
Primary care physicians began prescribing antacid therapy for chronic cough
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NCT03794596
2018-004121-80
Details
2019-07-22
Interventional
20 
Aspirin Avelumab Dexlansoprazole Lansoprazole Proton Pump Inh…
Breast Neoplasm… Triple Negative… Breast Cancer
IP breach
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NCT03855865
2018-000063-88
Details
2019-07-19
Interventional
30 
Vortioxetine
Depression Depressive Diso… Depressive Diso…
Business decision to stop the program.
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