Friedrichs, M. (2023). A web-based annotation tool for clinical trial failure reasons. GMS Medizinische Informatik, Biometrie Und Epidemiologie, 19, Doc02. doi: 10.3205/mibe000241

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7805 Trials matched filter criteria

Status:   Withdrawn   Suspended   Terminated
Trial Updated /
Type
Status Phase Were
Results
Reported
Reported
Actual
Enrollment
(MeSH) Terms Why Stopped
Limitations And Caveats
Annotator decisions
NCT02737072
Details
2019-08-12
Interventional
19 
Durvalumab
Neoplasms Solid Tumor
-
The study was terminated after the Phase 1a part was complete.
NCT00476996
2006-005330-20
Details
2019-08-12
Interventional
3836 
Leflunomide Methotrexate Ocrelizumab
Arthritis Arthritis, Rheu… Rheumatoid Arth…
Recruitment was fully completed for this study; however, the study was terminated during conduct after the primary endpoint analysis was completed.
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NCT01619566
Details
2019-08-09
Interventional
40 
Duloxetine Hydr…
Fibromyalgia Myofascial Pain…
Sponsor related
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NCT03777579
Details
2019-08-08
Interventional
3-
Albumin-Bound P… Antibodies Immunoglobulins Paclitaxel
Breast Neoplasm… Triple Negative… Triple Negative…
trial handovered to another sponser.
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NCT03014297
Details
2019-08-08
Interventional
117 
Everolimus Fosbretabulin
Neuroendocrine … Everolimus
Part I completed. Part 2 will not be done due to sponsor decision.
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NCT02983604
2016-002365-63
Details
2019-08-07
Interventional
1/214 
Exemestane Fulvestrant
Breast Neoplasm… Advanced Estrog…
-
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NCT02933814
Details
2019-08-07
Interventional
30 
Bupivacaine
Pain
Inadequate number of subjects meet study criteria
-
NCT02634827
Details
2019-08-07
Interventional
21 
Decitabine Midostaurin Staurosporine
Leukemia Leukemia, Myelo… Leukemia, Myelo… Acute Myeloid L… Acute Myeloid L… FLT3 Tyrosine K… Secondary Acute… Untreated Adult…
-
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NCT01465464
Details
2019-08-07
Interventional
3888 
Orantinib
Carcinoma Carcinoma, Hepa… Hepatocellular …
-
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NCT00291408
2005-003297-13
Details
2019-08-07
Interventional
40 
Nitric Oxide
Lung Diseases, … Pulmonary Disea… Age Matched Hea… Chronic Obstruc…
Researchers left the institute
-
NCT03429556
Details
2019-08-05
Interventional
223 
Botulinum Toxin…
Musculoskeletal… Abdominoplasty
Sponsor decision to terminate early
-
NCT01822496
Details
2019-08-05
Interventional
259 
Albumin-Bound P… Carboplatin Cisplatin Crizotinib Erlotinib Hydro… Etoposide Etoposide phosp… Paclitaxel Podophyllotoxin Tyrosine Kinase…
Carcinoma, Non-… Lung Neoplasms Stage III Non-S… Stage IIIA Non-… Stage IIIB Non-…
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This study stopped accrual early due to unmet targeted accrual goals with 59 subjects accrued out of 234 planned.
NCT00517491
Details
2019-08-05
Interventional
20 
Lanreotide
Acromegaly
Administrative reasons
-
NCT03781375
Details
2019-08-02
Interventional
325 
Etanercept Methotrexate
Arthritis Arthritis, Juve… Arthritis, Rheu… Juvenile Rheuma…
-
-
NCT00837590
Details
2019-08-01
Interventional
116 
Salicylsalicyli… Sodium Salicyla…
Glucose Intoler… Inflammation Obesity Prediabetic Sta… Pre-diabetes
Preliminary results indicated no measurable benefit.
This study was a small pilot not powered for main outcomes; the goal was to gather preliminary data for future grants.
NCT03391050
Details
2019-07-31
Interventional
1/23 
Dabrafenib
Melanoma
Target patient population - difficult to find patientes
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NCT02531633
Details
2019-07-31
Interventional
3161 
Antibodies, Mon… Prednisone
Arteritis Giant Cell Arte… Polymyalgia Rhe…
GSK decision to return rights to sirukumab to Janssen and discontinue sirukumab development in giant cell arteritis.
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NCT03418571
Details
2019-07-30
Interventional
215 
Gontivimab
Communicable Di… Infections Respiratory Tra… Respiratory Syn…
The Sponsor decided to discontinue ALX-0171 development (due to insufficient evidence of efficacy). As a result, the ALX0171-C203 study was early terminated.
Based on the results of the Phase IIb study ALX0171-C201 (RESPIRE), the Sponsor decided to discontinue ALX-0171 development in infants and to early terminate the ALX0171-C203 study. Therefore, no data are available for the higher dose groups.
NCT02769130
Details
2019-07-30
Interventional
1/2-
Losartan
Constriction, P… Stenosis, Pulmo… Children Pulmonary Vein …
Due to Health Canada losartan recall, a new formulation being added to the protocol/ temporary suspension
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NCT02707328
Details
2019-07-30
Interventional
1-
Gemcitabine Paclitaxel
Adenocarcinoma Pancreatic Neop… Adenocarcinoma … Pancreas Adenoc… Pancreas Cancer Pancreatic Aden… Pancreatic Canc…
Closed after being on administrative hold
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