Friedrichs, M. (2023). A web-based annotation tool for clinical trial failure reasons. GMS Medizinische Informatik, Biometrie Und Epidemiologie, 19, Doc02. doi: 10.3205/mibe000241

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7805 Trials matched filter criteria

Status:   Withdrawn   Suspended   Terminated
Trial Updated /
Type
Status Phase Were
Results
Reported
Reported
Actual
Enrollment
(MeSH) Terms Why Stopped
Limitations And Caveats
Annotator decisions
NCT03126864
Details
2019-11-04
Interventional
111 
Cyclophosphamid… Fludarabine Fludarabine pho…
Leukemia Leukemia, Myelo… Leukemia, Myelo… Acute Myeloid L… Hematopoietic/L…
Terminated per the PI's request.
-
NCT02553499
Details
2019-11-04
Interventional
137 
Pembrolizumab
Neoplasms Advanced Solid …
Enrollment prematurely discontinued due to program prioritization & not due to any safety concerns.
Enrollment into this study was prematurely discontinued due to program prioritization and not related to any safety concerns.
NCT01264887
2009-013291-46
Details
2019-11-04
Interventional
331 
Tapentadol
Cancer Pain Chronic Pain Neoplasms Cancer Pain
Administrative reasons
The trial was stopped for administrative reasons. Three years after trial initiation 2 participants were in the trial and to permit analysis and reporting the sponsor decided to terminate the trial.
NCT01135537
Details
2019-11-04
Interventional
230 
Antilymphocyte … Thymoglobulin
Genetic Disease… Metabolic Disea… Genetic Disorde… Malignancy Metabolic Disea…
The study was closed before 2017 due to inconclusive results from Lab
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NCT00859456
Details
2019-11-04
Interventional
210 
Sunitinib
Sarcoma Sarcoma, Soft T…
Closed by pharmaceutical sponsor
-
NCT00547118
Details
2019-11-04
Interventional
217 
Rimonabant
Psychotic Disor… Schizophrenia Hypertension Obesity Schizoaffective… Smoking
Withdrawn due to medication withdrawal from the EMEA
-
NCT03374709
Details
2019-11-01
Interventional
40 
Oxcarbazepine
Neuralgia Trigeminal Neur…
Resource and time constraints were encountered by product manufacturer and study team.
-
NCT03280342
Details
2019-11-01
Interventional
20 
Topiramate
Headache Migraine Disord… Migraine
Sponsor terminated study
-
NCT02267707
Details
2019-11-01
Interventional
11 
Gemcitabine Paclitaxel
Cholestasis Hyperbilirubine… Pancreatic Neop…
Study population more infrequent than estimated. No study-related safety issues and no safety concerns were identified for the study.
-
NCT03345940
2017-000559-26
Details
2019-10-31
Interventional
455 
Dimethyl Fumara… Fingolimod Hydr…
Multiple Sclero… Multiple Sclero… Sclerosis Relapsing Remit…
termination of the study due to the slowness of the recruitment activity, according to the contract signed with the Sponsor
-
NCT00850993
2009-017434-45
Details
2019-10-30
Interventional
258 
Tin mesoporphyr…
Hyperbilirubine… Hyperbilirubine…
To redefine study population
It should be noted that the study was discontinued before enrollment of the full 4.5 mg/kg cohort,and therefore, the stannsoporfin 4.5 mg/kg treatment group included 8 patients and the placebo group included 15 patients.
NCT03697824
Details
2019-10-29
Interventional
20 
Cyclophosphamid… Fludarabine Pembrolizumab
Sarcoma Sarcoma, Synovi… Neoplasms
Internal decision, study will be replaced with a larger monotherapy trial
-
NCT03610100
Details
2019-10-29
Interventional
2/3-
Gemcitabine
Carcinoma Carcinoma, Acin… Pancreatic Neop… Pancreatic Acin…
Suspended to recruitment following TSC review on efficacy and toxicities
-
NCT03504033
Details
2019-10-29
Interventional
40 
Desflurane
Liver Function …
A device would have had to be maintained. The maintenance company is insolvent; both another maintenance company and another serviced device were not available.
-
NCT02448251
Details
2019-10-29
Interventional
128 
Abivertinib
Carcinoma, Non-… Lung Neoplasms Non Small Cell …
-
-
NCT01832350
Details
2019-10-29
Interventional
434 
Dextromethorpha… Quinidine
Alzheimer Disea… Alzheimer's Dis… Pseudobulbar Af…
Sponsor decided to stop study early
-
NCT03965624
2018-004556-38
Details
2019-10-28
Interventional
20 
Ixazomib
Anemia, Hemolyt… Anemia, Hemolyt… Cytopenia Purpura, Thromb… Thrombocytopeni… Immune Thromboc… Warm Autoimmune…
Decision of sponsor: impossibility of contract with Takeda
-
NCT02007447
Details
2019-10-28
Interventional
2/330 
Oxytocin
Autism Spectrum… Autistic Disord… Child Developme…
Most of our patients had no willingness to participate in the survey
-
NCT01485094
2011-002092-42
Details
2019-10-28
Interventional
2114 
Pregabalin
Neuralgia
The trial was early terminated after it was concluded that there was no added benefit from exposing further participants after an unblinded interim analysis.
-
NCT01024686
Details
2019-10-28
Interventional
1/2
[1 Refs]
6 
Vaccines
Malaria
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