Friedrichs, M. (2023). A web-based annotation tool for clinical trial failure reasons. GMS Medizinische Informatik, Biometrie Und Epidemiologie, 19, Doc02. doi: 10.3205/mibe000241

Filter:

Trial ID Phase Status Type
Results Reported Result Refs Exist Enrollment From To
Free Text
Annotations

7805 Trials matched filter criteria

Status:   Withdrawn   Suspended   Terminated
Trial Updated /
Type
Status Phase Were
Results
Reported
Reported
Actual
Enrollment
(MeSH) Terms Why Stopped
Limitations And Caveats
Annotator decisions
NCT04058964
Details
2020-03-13
Interventional
20 
Pembrolizumab
Pancreatic Neop… Metastatic Panc… Stage IV Pancre…
Study withdrawn by supporter
-
NCT03580694
Details
2020-03-13
Interventional
117 
Cemiplimab
Carcinoma, Non-… Lung Neoplasms
Program reprioritization
-
NCT02819999
Details
2020-03-12
Interventional
128 
Etoposide Rovalpituzumab …
Lung Neoplasms Small Cell Lung… Small Cell Lung…
Strategic considerations
-
NCT02756728
Details
2020-03-12
Interventional
1/25 
Melphalan
Multiple Myelom… Neoplasms, Plas…
Full clinical hold from FDA
-
NCT03529929
Details
2020-03-11
Interventional
30 
Methylprednisol… Methylprednisol… Methylprednisol… Prednisolone Prednisolone ac… Prednisolone he… Prednisolone ph…
Inflammation Aging
withdrawn
-
NCT01094262
2009-016831-36
Details
2020-03-11
Interventional
2196 
Analgesics Oxycodone
Arthralgia Osteoarthritis Osteoarthritis,… Joint Pain Pain
Logistic reasons associated with the FDA-imposed clinical hold.
-
NCT02401542
2017-001319-36
Details
2020-03-09
Interventional
1/271 
Docetaxel
Carcinoma Urinary Bladder… Urologic Diseas… Locally Advance… Urinary Bladder… Urological Dise…
program has been put on hold by the sponsor
-
NCT03290196
Details
2020-03-06
Interventional
4-
Bupivacaine
Pain, Postopera… Rotator Cuff In… Rotator Cuff Te…
Patients pain was not regulated well with this product.
-
NCT03678090
Details
2020-03-05
Interventional
20 
Plasminogen Tissue Plasmino…
Lung Neoplasms Pleural Effusio… Pleural Effusio… Cancer, Lung
Local IRB recommended IND exemption from FDA, study timeline not able to be met.
-
NCT02875093
Details
2020-03-05
Interventional
123 
Cytarabine
Leukemia Leukemia, Myelo… Leukemia, Myelo… Acute Myeloid L…
Study Termination
-
NCT03862079
Details
2020-03-04
Interventional
20 
Nystatin Piperacillin Piperacillin, T… Tazobactam
Graft vs Host D… Graft-versus-ho…
Per PI's request
-
NCT02739360
2015-005766-39
Details
2020-03-04
Interventional
43 
Idelalisib
Neoplasms Lymphoid Malign…
-
-
NCT01742793
Details
2020-03-04
Interventional
112 
Lenalidomide Romidepsin
Hodgkin Disease Lymphoma Lymphoma, T-Cel… Lymphoma, T-Cel… Multiple Myelom… Neoplasms, Plas… Hodgkin's Lymph… Mature T-cell L…
The study was terminated due to withdrawal of institutional support, Phase II never began.
-
NCT04020653
Details
2020-03-03
Interventional
20 
Aminolevulinic … Artemether Artemisinin Artemisinins Citric Acid Ferrous citrate Lumefantrine Sodium Citrate
Malaria
Considering the Thai FDA requirement, changes of Malaria cases in Thailand and EC recommendation, the decision to withdrawal the study was made.
-
NCT02784483
Details
2020-03-03
Interventional
12 
Atezolizumab
Multiple Myelom… Neoplasms, Plas… Smoldering Mult… Asymptomatic My…
Based on FDA requirements
-
NCT01863719
Details
2020-03-02
Interventional
127 
Colistin
Pneumococcal In… Pneumonia Pathogen Resist… Pneumococcal In…
Completion of cohort 3, safety concerns
-
NCT00512044
Details
2020-03-02
Interventional
40 
Anesthetics
Hemorrhoids
slow recruitment, internal problems with the study protocol
-
NCT03278808
Details
2020-02-27
Interventional
2
[4 Refs]
0 
Atovaquone Atovaquone, pro… Azithromycin Chloroquine Chloroquine dip… Proguanil
Malaria
The IND has been withdrawn from FDA
-
NCT03019120
Details
2020-02-26
Interventional
20 
Vitamin D
Cognitive Dysfu… Vitamin D Defic… Neurocognitive …
Due to administrative reasons, it was not possible to enroll subjects.
-
NCT03498222
Details
2020-02-25
Interventional
10 
Atezolizumab Carboplatin Pemetrexed
Carcinoma, Non-…
Funder and IMP manufacturer withdrew support
-