Friedrichs, M. (2023). A web-based annotation tool for clinical trial failure reasons. GMS Medizinische Informatik, Biometrie Und Epidemiologie, 19, Doc02. doi: 10.3205/mibe000241

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Trial ID Phase Status Type
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7805 Trials matched filter criteria

Status:   Withdrawn   Suspended   Terminated
Trial Updated /
Type
Status Phase Were
Results
Reported
Reported
Actual
Enrollment
(MeSH) Terms Why Stopped
Limitations And Caveats
Annotator decisions
NCT02685111
Details
2020-07-31
Interventional
222 
Lenograstim
Breast Neoplasm… Febrile Neutrop… Neutropenia Breast Cancer
-
-
NCT02229175
Details
2020-07-31
Interventional
2/30 
Bevacizumab
Edema Macular Edema Diabetic Macula…
Study not feasible with current resources.
-
NCT00112749
Details
2020-07-31
Interventional
27 
Infliximab
Breast Neoplasm… Fatigue Breast Cancer
Recruitment stopped due to slow accrual and lack of evidence of need for further continuation of protocol in inpatient setting.
-
NCT02737202
Details
2020-07-30
Interventional
228 
Saracatinib
Lymphangioleiom… Pulmonary Lymph…
-
-
NCT02394106
Details
2020-07-29
Interventional
213 
Ofatumumab
Nephrosis Nephrotic Syndr… Syndrome
-
-
NCT01053507
Details
2020-07-29
Interventional
423 
Naproxen Sumatriptan
Cognitive Dysfu… Headache Post-Traumatic …
Enrollment rate was slower than anticipated.
-
NCT02926248
Details
2020-07-28
Interventional
4-
Colchicine
Manipulation Un…
Continuing IRB review was not submitted. Study was inactivated with the institutional IRB.
-
NCT00712270
Details
2020-07-28
Interventional
421 
Aripiprazole Risperidone
Schizophrenia
Study terminated due to failure to meet sufficient enrollment for valid analysis
Study was terminated back in 2009 with limited data available. Randomization is not known. Only 7 subjects completed study.
NCT01837069
Details
2020-07-27
Interventional
4198 
Angiotensin-Con… Atorvastatin Lisinopril Metoprolol
Cardiovascular … Cardiovascular … Osteoarthritis
Low recruitment / DSMB approval to halt recruitment
-
NCT00075673
Details
2020-07-27
Interventional
16 
Celecoxib Vinorelbine
Breast Neoplasm… Breast Cancer
-
-
NCT03014804
Details
2020-07-24
Interventional
20 
Nivolumab
Glioblastoma Gliosarcoma Oligodendroglio… Recurrence Giant Cell Glio… Recurrent Gliob… Small Cell Glio…
Final contract negotiations
-
NCT02247648
Details
2020-07-24
Interventional
2100 
Tramadol
Pruritus Vertigo Nausea Pain
-
-
NCT02899156
Details
2020-07-23
Interventional
422 
Flumazenil
Delirium Hypokinesia Hypoactive Deli…
A planned interim analysis led to the trial being stopped early based on the observed size effect and power analysis.
A planned interim analysis led to the trial being stopped early based on the observed size effect and power analysis.
NCT01445821
Details
2020-07-23
Interventional
344 
Cyclophosphamid… Fludarabine Methylprednisol… Methylprednisol… Thymoglobulin
Scleroderma, Di… Scleroderma, Sy…
Developed a better regimen: DIAD. Cast. 2018 NCT03593902
-
NCT03877692
Details
2020-07-22
Interventional
410 
Labetalol
Hypertension Pre-Eclampsia Chronic Hyperte… Preeclampsia Wi…
Slow enrollment
-
NCT03872336
Details
2020-07-22
Interventional
4
[1 Refs]
15 
Labetalol
Pre-Eclampsia Preeclampsia Wi…
Slow enrollment
-
NCT02781467
Details
2020-07-22
Interventional
110 
Cyclophosphamid… Fludarabine Interleukin-2
Leukemia Leukemia, Myelo… Leukemia, Myelo…
Business Decision
-
NCT02412371
2016-001659-32
Details
2020-07-22
Interventional
1/248 
Carboplatin Paclitaxel Veliparib
Carcinoma, Non-… Lung Neoplasms Non-small Cell …
Phase 2 was not conducted due to a change in the standard of care for newly diagnosed, unresectable Stage III NSCLC
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NCT01425307
Details
2020-07-22
Interventional
3159 
Hydroxyurea
Anemia Anemia, Sickle … Sickle Cell Ane…
The study was stopped early due to successfully meeting the primary endpoint
Further analysis is required to verify that the Adverse Events are accurately represented.
NCT00640094
2005-000821-49
Details
2020-07-22
Interventional
2
[1 Refs]
272 
Melatonin
Infarction Myocardial Infa… Acute Myocardia…
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