Friedrichs, M. (2023). A web-based annotation tool for clinical trial failure reasons. GMS Medizinische Informatik, Biometrie Und Epidemiologie, 19, Doc02. doi: 10.3205/mibe000241

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7805 Trials matched filter criteria

Status:   Withdrawn   Suspended   Terminated
Trial Updated /
Type
Status Phase Were
Results
Reported
Reported
Actual
Enrollment
(MeSH) Terms Why Stopped
Limitations And Caveats
Annotator decisions
NCT03073850
Details
2020-09-09
Interventional
448 
Anticoagulants Clopidogrel Edoxaban
Atrial Fibrilla…
Majority of enrolled patients have withdrawn.
-
NCT02790996
Details
2020-09-09
Interventional
2242 
Vancomycin
Neonatal Sepsis Sepsis Late Onset Neon…
Planned interim analysis yielded different event rate affecting sample size and ability to recruit sufficient numbers within remaining trial time frame
-
NCT02501473
2015-005382-23
Details
2020-09-09
Interventional
1/252 
Pembrolizumab Rituximab
Lymphoma Lymphoma, Folli… Lymphoma, Non-H… Follicular Low …
Business reasons
The study was terminated (halted prematurely) for business reasons.
NCT01859741
Details
2020-09-09
Interventional
1/2172 
Carboplatin Etoposide
Lung Neoplasms Small Cell Lung… Stage IV Small …
OMP-59R5 did not improve PFS.
-
NCT04522466
2020-001281-11
Details
2020-09-07
Interventional
37 
Hydroxychloroqu…
COVID-19 Sars-CoV2
Stop of the study by competent authority (ANSM)
-
NCT04106843
Details
2020-09-07
Interventional
20 
Lutetium Lu 177…
Carcinoma Carcinoma, Medu… Carcinoma, Neur… Paraganglioma Pheochromocytom… Pituitary Disea… Thyroid Disease… Thyroid Neoplas… Locally Advance… Locally Advance… Metastatic Adre… Metastatic Para… Metastatic Para… Pituitary Gland… Somatostatin Re… Stage III Thyro… Stage IV Thyroi… Stage IVA Thyro… Stage IVB Thyro… Stage IVC Thyro… Unresectable Ad… Unresectable Pa…
No Participants Registered
-
NCT03750656
Details
2020-09-07
Interventional
46 
Hyoscyamine Tamsulosin
Lower Urinary T…
Not accruing patients quickly enough
-
NCT03657095
Details
2020-09-07
Interventional
3112 
Beraprost
Familial Primar… Hypertension Pulmonary Arter…
The pivotal study, BPS-314d-MR-PAH-302 (NCT01908699), failed to demonstrate efficacy.
The study was terminated early due to the pivotal study, BPS-314d-MR-PAH-302 (NCT01908699), failed to demonstrate efficacy.
NCT03133897
Details
2020-09-07
Interventional
320 
Dexamethasone Prednisone
Asthma
it was felt by the sponsoring institution that the current standard of oversight expected by the Health Canada regulations, would not be possible to achieve
-
NCT04392128
2020-002002-45
Details
2020-09-04
Interventional
20 
Azithromycin Hydroxychloroqu…
COVID-19 Hematologic Neo… Neoplasms COVID19 Hematologic Mal…
competent authority decision
-
NCT04249713
Details
2020-09-04
Interventional
10 
Brodalumab
Hidradenitis Hidradenitis Su…
Biomarker Samples Not Collected
-
NCT02607488
Details
2020-09-04
Interventional
1/2-
Lidocaine
Bariatric Surge… Obesity
No fund no enough recruiting centers
-
NCT02057523
Details
2020-09-04
Interventional
42 
Adrenocorticotr… Hormones Melanocyte-Stim… beta-Endorphin
Proteinuria Transplant Glom…
Unable to enroll patients, no longer at institution.
-
NCT01861561
Details
2020-09-04
Interventional
443 
Cyclophosphamid…
Renal Insuffici… Infection
The duration of the study is longer than 5 years and we can not recruit the participants to the target number.
-
NCT03978884
Details
2020-09-03
Interventional
40 
Amlodipine Hydrochlorothia… Losartan
Hypertension Diabetes Mellit…
Unable to effective arrange trial logistics
-
NCT02638506
Details
2020-09-03
Interventional
462 
Fentanyl
Headache Headaches
Covid restrictions
-
NCT01978366
Details
2020-09-03
Interventional
217 
Halofuginone
Muscular Dystro… Muscular Dystro… Duchenne Muscul…
Dosing stopped
-
NCT01847573
Details
2020-09-03
Interventional
1/217 
Halofuginone
Muscular Dystro… Muscular Dystro… Duchenne Muscul…
Dosing stopped
-
NCT01367275
Details
2020-09-03
Interventional
28 
Irinotecan
Adenocarcinoma Colorectal Neop… Colorectal Aden… Colorectal Canc…
Sponsor closed study
As a result of the drug sponsor closing study early, the accrual goal was not met and with the small number of participants enrolled no statistical analysis or conclusions was possible from the data.
NCT00486512
Details
2020-09-03
Interventional
3350 
Aspirin Calcitriol Calcium Calcium Carbona… Calcium, Dietar… Dihydroxycholec…
Adenoma Adenomatous Pol…
The overall program was terminated
-