Friedrichs, M. (2023). A web-based annotation tool for clinical trial failure reasons. GMS Medizinische Informatik, Biometrie Und Epidemiologie, 19, Doc02. doi: 10.3205/mibe000241

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7805 Trials matched filter criteria

Status:   Withdrawn   Suspended   Terminated
Trial Updated /
Type
Status Phase Were
Results
Reported
Reported
Actual
Enrollment
(MeSH) Terms Why Stopped
Limitations And Caveats
Annotator decisions
NCT05184101
Details
2024-02-26
Interventional
2/30 
Calcium heparin Heparin
COVID-19
COVID-19 hospitalisations limited in Australia, unable to recruit patients due to low numbers of hospitalisations.
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NCT05093517
Details
2024-02-26
Interventional
1-
Volagidemab
Diabetes Mellit… Glucose Intoler… Insulin Resista… Glucose Toleran… Insulin Sensiti… Type 2 Diabetes
Temporarily closed to enrollment, pending funding
-
NCT05065411
Details
2024-02-26
Interventional
35 
Everolimus Exemestane Fulvestrant
Breast Neoplasm… Metastatic Brea…
Business decision
-
NCT04912063
2021-000514-41
Details
2024-02-26
Interventional
140 
Azacitidine Venetoclax
Leukemia Leukemia, Myelo… Leukemia, Myelo… Myelodysplastic… Preleukemia Syndrome Acute Myeloid L… Myelodysplastic…
Strategic considerations
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NCT03221751
Details
2024-02-26
Interventional
49 
Prazosin
Dementia
staffing issues and COVID
These results are not generalizable due to the small sample size.
NCT05679479
Details
2024-02-23
Interventional
3108 
Meplazumab
COVID-19
According to the covid-19 epidemic situation in China, there is few sever covid-19 patients.
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NCT05571267
Details
2024-02-23
Interventional
21 
Aflibercept Bevacizumab Ranibizumab
Macular Degener…
Following Sponsor reassessment, OPH2004 enrollment was stopped to initiate a new Zimura wet AMD trial, OPH2007, for treatment-naïve patients. Thus, only one patient was enrolled into and completed Study OPH2004.
Following the Sponsor's reassessment of the Zimura development program, enrollment was stopped in this trial as the Sponsor determined that they would initiate a new Zimura wet AMD trial, the OPH2007 trial, for treatment-naïve patients. Therefore, a total of two patients were screened, one of whom was a screen failure. Thus, only one patient was enrolled into Study OPH2004.
NCT05357898
Details
2024-02-23
Interventional
1/220 
Pembrolizumab
Neoplasms Adult Solid Tum…
Corporate Decision
-
NCT05345938
Details
2024-02-23
Interventional
1/21 
Mitoxantrone
Leukemia Leukemia, Myelo… Leukemia, Myelo… Relapsed or Ref…
Adjust the research strategy.
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NCT05209529
2022-003594-33
Details
2024-02-23
Interventional
20 
Durvalumab Olaparib
Breast Neoplasm… Triple Negative… BRCA1 Mutation BRCA2 Mutation TNBC - Triple-N…
Withdrawn interest from grant provider
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NCT05116774
2020-004438-39
Details
2024-02-23
Interventional
212 
Eculizumab Ravulizumab
Hemoglobinuria Hemoglobinuria,… Paroxysmal Noct…
Sponsor decision
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NCT04927481
Details
2024-02-23
Interventional
228 
Mitoxantrone
Breast Neoplasm… Breast Cancer
The sponsor has adjusted its R&D strategy.
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NCT04892043
Details
2024-02-23
Interventional
15 
Ipilimumab Nivolumab
Neoplasms Adult Solid Tum…
Corporate Decision
-
NCT04489732
Details
2024-02-23
Interventional
16 
Interferon-gamm… Interferons
Head and Neck N… Xerostomia Xerostomia Foll…
Unanticipated event
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NCT03709706
Details
2024-02-23
Interventional
1/234 
Pembrolizumab
Carcinoma, Non-… Lung Neoplasms Neoplasms
The study was terminated for reasons pertaining to feasibility
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NCT02387957
Details
2024-02-23
Interventional
263 
Aflibercept Bevacizumab Ranibizumab
Macular Degener… Age-Related Mac…
-
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NCT02214628
Details
2024-02-23
Interventional
2101 
Becaplermin
Macular Degener… Age-related Mac…
-
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NCT01944839
Details
2024-02-23
Interventional
3619 
Ranibizumab
Macular Degener… Age-Related Mac…
-
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NCT01940900
Details
2024-02-23
Interventional
3627 
Ranibizumab
Macular Degener… Age-Related Mac…
-
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NCT01940887
Details
2024-02-23
Interventional
3645 
Aflibercept Bevacizumab
Macular Degener… Age-Related Mac…
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