Friedrichs, M. (2023). A web-based annotation tool for clinical trial failure reasons. GMS Medizinische Informatik, Biometrie Und Epidemiologie, 19, Doc02. doi: 10.3205/mibe000241

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Trial ID Phase Status Type
Results Reported Result Refs Exist Enrollment From To
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7805 Trials matched filter criteria

Status:   Withdrawn   Suspended   Terminated
Trial Updated /
Type
Status Phase Were
Results
Reported
Reported
Actual
Enrollment
(MeSH) Terms Why Stopped
Limitations And Caveats
Annotator decisions
NCT03339921
Details
2024-03-05
Interventional
2/33 
Botulinum Toxin…
Chronic Exertio… Compartment Syn… Syndrome
This study is being closed because it is unworkable.
This study was terminated because it is unworkable.
NCT03151707
Details
2024-03-05
Interventional
411 
Niacin Niacinamide Nicotinic Acids
Healthy
Lack of funding and appropriate staff
Early termination leading to small numbers of subjects analyzed
NCT02261883
Details
2024-03-05
Interventional
242 
Treprostinil
Hypertension Hypertension, P… Persistent Feta… Persistent Pulm…
Sponsor Decision
-
NCT02013167
2013-000536-10
Details
2024-03-05
Interventional
3405 
Blinatumomab
Leukemia Leukemia, Lymph… Precursor Cell … Relapsed/Refrac…
-
-
NCT05617313
Details
2024-03-04
Interventional
2-
Pembrolizumab
Carcinoma, Non-… Lung Neoplasms Metastatic NSCL… Non Small Cell … Recurrent Non S…
Interim Analysis
-
NCT05461794
Details
2024-03-04
Interventional
296 
Docetaxel Irinotecan Tislelizumab
Carcinoma Carcinoma, Squa… Esophageal Squa…
Due to modification of company strategy.
-
NCT04314843
2019-004568-23
Details
2024-03-04
Interventional
16 
Axicabtagene ci… Cyclophosphamid… Fludarabine Lenzilumab
Lymphoma Lymphoma, B-Cel… Relapsed/Refrac…
Development program terminated and the decision was not due to any safety concerns.
-
NCT04152863
2019-002034-36
Details
2024-03-04
Interventional
285 
Pembrolizumab
Melanoma Advanced/Metast…
Business Reasons
-
NCT03863288
Details
2024-03-04
Interventional
1/260 
Oxytocin
Irritable Mood
Per DSMB's recommendation
-
NCT03319537
Details
2024-03-04
Interventional
1/29 
Pemetrexed Pevonedistat
Mesothelioma Mesothelioma, M…
Sponsor terminated study agreement
-
NCT02735343
Details
2024-03-04
Interventional
35 
Ketamine Prochlorperazin…
Emergencies Headache
study goals met
This study was terminated early due to the study becoming unnecessary due to findings in another trial.
NCT01156922
Details
2024-03-04
Interventional
2
[1 Refs]
8 
Rituximab
Encephalomyelit… Fatigue Fatigue Syndrom… Myalgia Syndrome Chronic Fatigue… Myalgic Encepha…
Difficulties in logistics handling the very severe patients (travel, hospital stay, follow-up)
-
NCT00019695
NCT00001802
Details
2024-03-04
Interventional
2-
Alendronate Ketoconazole
Adenocarcinoma Neoplasm Metast… Prostatic Neopl… Adenocarcinoma … Bone Metastases Recurrent Prost… Stage IV Prosta…
-
-
NCT00003552
NCT00001739
Details
2024-03-04
Interventional
1/2-
Antilymphocyte … Cyclophosphamid… Fludarabine
Melanoma Recurrent Melan… Stage IV Melano…
-
-
NCT05374603
Details
2024-03-01
Interventional
2-
Durvalumab
Lung Cancer
The sponsor needs to comprehensively evaluate the benefit and risk of the study.
-
NCT05124691
Details
2024-03-01
Interventional
2/3992 
Albendazole Ivermectin
Helminthiasis Helminthes; Inf…
Primary Endpoint met
-
NCT04920383
Details
2024-03-01
Interventional
129 
Pembrolizumab
Neoplasms Advanced Solid … Lymphoma
Sponsor decision
-
NCT04128956
2019-001723-12
Details
2024-03-01
Interventional
2172 
Aspirin
Thrombosis Venous Thrombos… Stent Stenosis Venous Thrombos…
Recommendation by DSMB
-
NCT03806751
Details
2024-03-01
Interventional
10 
Acetazolamide
Validation of a…
The investigator decided not to pursue the study.
-
NCT03781986
Details
2024-03-01
Interventional
1/2-
Carboplatin
Salivary Gland … Malignant Saliv… Salivary Gland …
enrollment has been placed on hold, pending evaluability assessment
-