Friedrichs, M. (2023). A web-based annotation tool for clinical trial failure reasons. GMS Medizinische Informatik, Biometrie Und Epidemiologie, 19, Doc02. doi: 10.3205/mibe000241

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7805 Trials matched filter criteria

Status:   Withdrawn   Suspended   Terminated
Trial Updated /
Type
Status Phase Were
Results
Reported
Reported
Actual
Enrollment
(MeSH) Terms Why Stopped
Limitations And Caveats
Annotator decisions
NCT03388164
Details
2021-09-16
Interventional
223 
Citalopram Dexetimide Escitalopram
Depression Depressive Diso…
The study was terminated early based on the planned interim analysis that did not meet criteria for continuation.
The study was terminated early based on the planned interim analysis.
NCT04745663
2019-001179-35
Details
2021-09-14
Interventional
4150 
Cadexomer iodin… Iodine Povidone Povidone-Iodine
Eye Infections
Not the expected 2/3 but only 1/3 of conjunctiva samples got bacterial growth. Lack of resources to keep the study going with more participants and over a considerably longer time than anticipated.
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NCT01899170
2013-002385-39
Details
2021-09-14
Interventional
23 
Carfentanil
Neuralgia
Device for multi coil TMS no longer supported
-
NCT04446637
Details
2021-09-13
Interventional
30 
Albuterol Ipratropium
Lung Diseases Lung Diseases, … Pulmonary Disea… Chronic Obstruc…
administrative decision
-
NCT01548144
Details
2021-09-13
Interventional
1178 
Crizotinib Pemetrexed
Neoplasms Advanced Cancer…
PI request
-
NCT04322682
Details
2021-09-08
Interventional
34506 
Colchicine
Coronavirus Inf… Corona Virus In…
Due to several considerations (logistical, human and budgetary), the study was stopped early.
Due to several considerations (logistical, human and budgetary), the study was stopped early. Furthermore, stopping the study after approximately 4500 patients had completed their 30-day follow-up would allow to communicate results in January 2021 in the hope of preventing complications of COVID-19 in ambulatory patients, instead of delivering results anywhere between April and October 2021 at a time when vaccination efforts might be successful.
NCT03563040
2018-001685-42
Details
2021-09-08
Interventional
20 
Methoxsalen
Lymphoma, T-Cel… Lymphoma, T-Cel… Mycoses Mycosis Fungoid… Sezary Syndrome Mycosis Fungoid…
Lack of feasibility
-
NCT02959554
2016-002170-13
Details
2021-09-08
Interventional
249 
Nivolumab Sunitinib
Carcinoma Carcinoma, Rena… Metastatic Rena…
-
-
NCT03892889
Details
2021-09-05
Interventional
3277 
Aripiprazole
Schizophrenia
Study has stopped for having met the primary endpoint.
-
NCT03806231
Details
2021-09-05
Interventional
38 
Dinoprostone
Induction of La…
Sponsor declined to provide further funding/product support.
Trial terminated prior to meeting sufficient sample size for outcome analyses.
NCT03608618
Details
2021-09-05
Interventional
114 
Cyclophosphamid…
Adenocarcinoma Carcinoma, Ovar… Mesothelioma Mesothelioma, M… Adenocarcinoma … Fallopian Tube … Peritoneal Meso… Primary Periton…
Sponsor shift in focus
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NCT02851004
Details
2021-09-05
Interventional
1/255 
Pembrolizumab
Colorectal Neop… Metastatic Colo…
On the request of the investigational drug provider. No subjects were newly enrolled in the additional cohort as they were preparing to resume enrollment in the additional cohort. Currently, it is preparing the creation of clinical study report.
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NCT02459613
Details
2021-08-26
Interventional
1/211 
Annexin A5
Endocarditis Thrombosis
-
-
NCT03696342
Details
2021-08-24
Interventional
346 
Gatifloxacin Pazufloxacin
Conjunctivitis Conjunctivitis,…
Sponsor's convenience
This trial was terminated early due to the sponsor's convenience in the pipeline followed by the studied product. A small sample renders this results as merely descriptive.
NCT03545165
Details
2021-08-24
Interventional
1/26 
Gallium 68 PSMA… Pluvicto
Prostatic Neopl… Prostate Cancer
Sponsor withdrawal
The study was terminated early due to sponsor withdrawal (PSMA-617 no longer available for purchase).
NCT00041691
Details
2021-08-19
Interventional
1-
Labetuzumab
Colorectal Neop…
-
-
NCT04430933
Details
2021-08-18
Interventional
1/20 
Carboplatin Docetaxel Paclitaxel Pemetrexed
Carcinoma, Non-… Lung Neoplasms Advanced or Met… Non-Small Cell …
Upon reviewing current available combo studies, the sponsor decided to prioritize different combo study.
-
NCT03352414
Details
2021-08-18
Interventional
284 
Alvimopan
Ileus
stopped by sponsor
-
NCT00644878
Details
2021-08-18
Interventional
218 
Nilotinib
Leukemia Leukemia, Myelo… Leukemia, Myelo… Leukemia, Myelo… Philadelphia Ch… Chronic Myeloge…
Slower than expected enrollment
The study was terminated on 31 March 2012 due to slower than planned enrollment, resulting in a small sample size, no inferential analyses were conducted.
NCT00881556
Details
2021-08-17
Interventional
13 
Alemtuzumab Busulfan Fludarabine Lorazepam Tacrolimus
Epidermolysis B… Epidermolysis B…
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