Friedrichs, M. (2023). A web-based annotation tool for clinical trial failure reasons. GMS Medizinische Informatik, Biometrie Und Epidemiologie, 19, Doc02. doi: 10.3205/mibe000241

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Trial ID Phase Status Type
Results Reported Result Refs Exist Enrollment From To
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Annotations

16247 Trials matched filter criteria

Status:   Withdrawn   Suspended   Terminated
Trial Updated /
Type
Status Phase Were
Results
Reported
Reported
Actual
Enrollment
(MeSH) Terms Why Stopped
Limitations And Caveats
Annotator decisions
NCT05536037
Details
2024-04-19
Interventional
14 
Metformin
Erythroplasia Leukoplakia Precancerous Co… Erythroplakia Oral Cavity Car… Proliferative V…
Slow accrual
-
1 annotator(s) decided:
DODTDSDWFUFRPIOC19
NCT05411107
Details
2024-04-19
Interventional
20 
Iloprost
Carcinoma Lung Diseases, … Lung Neoplasms Pulmonary Disea… Bronchial Epith… Chronic Obstruc… Lung Carcinoma Stage I Lung Ca… Stage II Lung C… Tobacco-Related…
Agent is not available
-
1 annotator(s) decided:
DODTDSDWFUFRPIOC19
NCT05213143
Details
2024-04-19
Interventional
413 
Lurasidone Hydr…
Schizophrenia
Company's business decision
-
NCT05040568
Details
2024-04-19
Interventional
1-
Cetuximab Cyclophosphamid… Fludarabine Fludarabine pho…
Neoplasm, Resid… Colon Cancer Resected Stage
DMC Monitor Action
-
NCT04949191
Details
2024-04-19
Interventional
210 
Pembrolizumab
Neoplasms Advanced Malign…
A business decision due to availability of commercial drug and other options for accessing study drug treatment.
-
NCT04613518
2019-004878-26
Details
2024-04-19
Interventional
238 
Deucravacitinib
Colitis Colitis, Ulcera… Ulcer
Trial terminated because of lack of efficacy in the short term acute phase.
-
1 annotator(s) decided:
DODTDSDWFUFRPIOC19
NCT04149574
Details
2024-04-19
Interventional
313 
BCG Vaccine Nivolumab
Non-Muscle Inva… Urinary Bladder…
Insufficient enrollment, inability to meet protocol objectives, and slow accrual.
-
NCT03801525
Details
2024-04-19
Interventional
2/3277 
Venetoclax
Leukemia Leukemia, Lymph… Leukemia, Lymph… Chronic Lymphoc… Small Lymphocyt…
Strategic/Business decision
Due to sponsor's business decision, the clinical trial was terminated by the sponsor prematurely. As such, the study results are reflective of the data captured to the time of study termination and with limited data verification.
NCT03474614
Details
2024-04-19
Interventional
24 
Propranolol
Congenital Abno… Hemangioma, Cav… Cerebral Cavern…
lack of accrual
-
1 annotator(s) decided:
DODTDSDWFUFRPIOC19
NCT03186456
Details
2024-04-19
Interventional
1-
Aspirin
Cerebral Infarc… Infarction
Others
-
NCT03184935
Details
2024-04-19
Interventional
1/2-
Decitabine
Myelodysplastic… Preleukemia Syndrome
Others
-
NCT03176498
Details
2024-04-19
Interventional
1/2-
Aspirin Atorvastatin Calcium
Cerebral Infarc… Infarction
Others
-
NCT02875223
Details
2024-04-19
Interventional
175 
Itraconazole Pulrodemstat be… Rifampin
Lymphoma Lymphoma, Non-H… Neoplasms
Business objectives have changed
-
NCT02276911
Details
2024-04-19
Interventional
26 
Ibuprofen
Opioid-Related … Pain, Postopera… Spondylosis Cervical Spondy… Lumbar Spondylo…
No enrollment
-
1 annotator(s) decided:
DODTDSDWFUFRPIOC19
NCT02085304
Details
2024-04-19
Interventional
1/28 
Temozolomide
Glioblastoma
met stopping rules for futility
-
1 annotator(s) decided:
DODTDSDWFUFRPIOC19
NCT05432804
Details
2024-04-18
Interventional
1/2-
Temozolomide
Glioblastoma Recurrence MGMT-Methylated… Recurrent Gliob… Recurrent MGMT-…
End of Initial Phase of Multi-phase protocol
-
NCT05264974
Details
2024-04-18
Interventional
1-
Vaccines
Melanoma Recurrence
major protocol revision in progress
-
NCT05177718
Details
2024-04-18
Interventional
41 
Natalizumab
Multiple Sclero… Sclerosis
Sponsor declined further support
-
NCT05159531
Details
2024-04-18
Interventional
42 
Emtricitabine Tenofovir
HIV Infections
Funding withdrawn
-
1 annotator(s) decided:
DODTDSDWFUFRPIOC19
NCT05104229
Details
2024-04-18
Interventional
30 
Aspirin
Crohn Disease Thromboembolism Venous Thromboe… Ulcerative Coli…
Limited Resources
-